ID A0A673CWN9_9TELE Unreviewed; 922 AA.
AC A0A673CWN9;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 18-JUN-2025, entry version 22.
DE SubName: Full=E3 ubiquitin-protein ligase RNF31-like {ECO:0000313|Ensembl:ENSSORP00005058009.1};
GN Name=LOC115410933 {ECO:0000313|Ensembl:ENSSORP00005058009.1};
OS Sphaeramia orbicularis (orbiculate cardinalfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Kurtiformes; Apogonoidei; Apogonidae; Apogoninae; Sphaeramia.
OX NCBI_TaxID=375764 {ECO:0000313|Ensembl:ENSSORP00005058009.1, ECO:0000313|Proteomes:UP000472271};
RN [1] {ECO:0000313|Ensembl:ENSSORP00005058009.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Wellcome Sanger Institute Data Sharing;
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSORP00005058009.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2025) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RBR family. {ECO:0000256|ARBA:ARBA00008278}.
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DR AlphaFoldDB; A0A673CWN9; -.
DR Ensembl; ENSSORT00005059331.1; ENSSORP00005058009.1; ENSSORG00005025639.1.
DR Proteomes; UP000472271; Chromosome 20.
DR GO; GO:0071797; C:LUBAC complex; IEA:InterPro.
DR GO; GO:0036435; F:K48-linked polyubiquitin modification-dependent protein binding; IEA:TreeGrafter.
DR GO; GO:0070530; F:K63-linked polyubiquitin modification-dependent protein binding; IEA:TreeGrafter.
DR GO; GO:1990450; F:linear polyubiquitin binding; IEA:TreeGrafter.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0097039; P:protein linear polyubiquitination; IEA:TreeGrafter.
DR CDD; cd20337; BRcat_RBR_HOIP; 1.
DR CDD; cd16631; mRING-HC-C4C4_RBR_HOIP; 1.
DR CDD; cd20351; Rcat_RBR_HOIP; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 1.20.58.2190; -; 1.
DR Gene3D; 6.10.140.1100; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047540; BRcat_RBR_RNF31-like.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR036339; PUB-like_dom_sf.
DR InterPro; IPR018997; PUB_domain.
DR InterPro; IPR047542; Rcat_RBR_RNF31-like.
DR InterPro; IPR026254; RNF31-like.
DR InterPro; IPR032065; RNF31-UBA.
DR InterPro; IPR041031; RNF31_C.
DR InterPro; IPR047541; RNF31_RBR_mRING-HC-like.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR16004:SF5; E3 UBIQUITIN-PROTEIN LIGASE RNF31; 1.
DR PANTHER; PTHR16004; RING FINGER PROTEIN 31-RELATED; 1.
DR Pfam; PF18091; E3_UbLigase_RBR; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF22191; IBR_1; 1.
DR Pfam; PF09409; PUB; 1.
DR Pfam; PF16678; UBA_HOIP; 1.
DR Pfam; PF25163; UBA_RNF31; 1.
DR SMART; SM00647; IBR; 2.
DR SMART; SM00547; ZnF_RBZ; 2.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF143503; PUG domain-like; 1.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50030; UBA; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 2.
DR PROSITE; PS50199; ZF_RANBP2_2; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000472271};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00322}.
FT DOMAIN 228..257
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 432..474
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 554..786
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 558..607
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 306..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..322
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 922 AA; 104266 MW; 87041F47B6B37004 CRC64;
HVNPVHPSPT CEQSLKIPLS ILEKYGCNLA SPTRPKYWRS VKHNNPVFRT TVDAVKGGRT
VLYLYGYTNQ QIDGLSFPDE VTEPDIEKVA AVTLEVMILR TEVDMIIKVC NRLSDSCKYL
SPFIPQSEEQ PADQPQVLSS SPKPCNLCGG PSSLVCPSCD SQSFCDACDD LFHRHPARAT
HKRDKIQKSK QGMSNIDALL LYVHYLWCFC DTCSVLDLCP ETMSQLPSLA PWECAHCTTV
NEMRAVLCTT CERPRLATAA SIVQETPASP NWTCQFCTYV NTKPTAVCEM CNLSCKDSAG
VSLPQSLQQT PTTTKDPQQP GMKPQPKPRV NPELKRQKLM KEEGLSLINH IREAEKRGVS
PEEVYAALCM CGGSNVNPCD WLMSELPHLL DEICAMAQIS TTGEGVKLSR AEAKLAWLAA
GGDTERAVKQ LLRDRQVKMR ELHSLGFRDV AQCEEALRQS GGEVKGALSL LQRPLLEPFH
QRIWANQPEP PIDPKHPDKQ RMCRRLLALY DLPSWGRCEL VLSLLQDPGI TYTLEDVVQA
VKESHDKDFI RRLLNNECPC CLSIFPRSKM QSLTSCQCSV CHECFGQHFT VAVRDKHIRD
MVCPVCSEPD INDQEQLDSY FSTLDIQLRD CLEHDVYDLF HKKLTEHALM KDPKFLWCCH
CTSGFINDGD HLKVTCPSCR KSFCAQCKKP WEPQHQDLSC EQFQQWKREN DPEYQRQGLA
GYLRDNGITC PHCRFQYALT KGGCMHFTCS QCRYQFCSGC NNPYHKTACK TPQCNYTGLH
AHHPRDCLFY LRDWEPARLQ ALLQKSGVEF NTDPSNETQT ANCGVMEQKD EGGLQIDSPC
GLETRPGQAG LCEKHYREYL VSLINAHSLD PAPLYDAQEV TRACERYQVD TQRGDEDDNA
YYTKLLKKLM EVPLGEKVPR NK
//
