ID A0A673FMW1_9TELE Unreviewed; 616 AA.
AC A0A673FMW1;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 28-JAN-2026, entry version 22.
DE RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN Name=LOC107711220 {ECO:0000313|Ensembl:ENSSRHP00000002073.1};
OS Sinocyclocheilus rhinocerous.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Cyprininae; Sinocyclocheilus.
OX NCBI_TaxID=307959 {ECO:0000313|Ensembl:ENSSRHP00000002073.1, ECO:0000313|Proteomes:UP000472270};
RN [1] {ECO:0000313|Ensembl:ENSSRHP00000002073.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSSRHP00000002073.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_016371646.1; XM_016516160.1.
DR RefSeq; XP_016371647.1; XM_016516161.1.
DR AlphaFoldDB; A0A673FMW1; -.
DR Ensembl; ENSSRHT00000002155.1; ENSSRHP00000002073.1; ENSSRHG00000001450.1.
DR GeneID; 107711220; -.
DR KEGG; srx:107711220; -.
DR OrthoDB; 8933073at2759; -.
DR Proteomes; UP000472270; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR InterPro; IPR039363; ZNF750.
DR InterPro; IPR039064; ZNF750_Znf.
DR PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR Pfam; PF15269; zf-C2H2_7; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000472270};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 5..58
FT /note="Zinc finger protein 750-like zinc finger"
FT /evidence="ECO:0000259|Pfam:PF15269"
FT REGION 60..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 549..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..335
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..438
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 549..562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..577
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..601
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 69618 MW; CD755BAF381388B5 CRC64;
MDTLQGRKPK KPHYIPRPPG KPFKYQCFQC PFTCNIKSHL FNHMKYNLCK NSISLVSQRM
EQTGKTPRAS QHNFPFNHKS KEPPLEDEAS KPTERINDKV EQEEMAKGTR EKPESPIKEV
TKYVPESIRE NRDKNADMDI GQNKISSAFS PVARTCESKA LSRSPHKDDQ SSSAIPQFYH
QMAPWVPPAS TAPLLPLIPD YPSYMVPERP LHSLYTPYSH SQANTPAYQL TPRETQRPLV
PSPLVPPNTS LLHPYHYRYG HSIIPGPPLP YSLYQHPELS MSLQRTRYLP LDVYSNRLYP
REYGEHLVPL SHPDSYGRLP EDRAFQEHST VDKGTRQSPL EGCAASGSPD RPSTADVTQR
IPVTFRHASH GESLPVNQSQ YADPGATTAT EILPKKSRGQ TQENMLQKKE RNEPQTTASA
RSSESSSEKE DEETEEEPVP LNLSKRDWAV SSNMTHHYPD RELHYDSESS QDEAPLNLCL
RVQSNNQALP NTTGSETPER QTIINAEVCT IVPPREQEID PCDQRHTAAF ALCQLASSKD
IINDSSIGQQ EKTEAQNSQS LPSPDKSPVK DTPDTPKQKS QALGQKRVIS RPLRHTTKRA
KVKEPARTQR KRSQNC
//
