ID A0A673JR87_9TELE Unreviewed; 614 AA.
AC A0A673JR87;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 28-JAN-2026, entry version 22.
DE RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN Name=znf750 {ECO:0000313|Ensembl:ENSSRHP00000052593.1};
OS Sinocyclocheilus rhinocerous.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Cyprininae; Sinocyclocheilus.
OX NCBI_TaxID=307959 {ECO:0000313|Ensembl:ENSSRHP00000052593.1, ECO:0000313|Proteomes:UP000472270};
RN [1] {ECO:0000313|Ensembl:ENSSRHP00000052593.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSSRHP00000052593.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016414274.1; XM_016558788.1.
DR AlphaFoldDB; A0A673JR87; -.
DR Ensembl; ENSSRHT00000054068.1; ENSSRHP00000052593.1; ENSSRHG00000026472.1.
DR GeneID; 107744962; -.
DR KEGG; srx:107744962; -.
DR CTD; 79755; -.
DR OrthoDB; 8933073at2759; -.
DR Proteomes; UP000472270; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR InterPro; IPR039363; ZNF750.
DR InterPro; IPR039064; ZNF750_Znf.
DR PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR Pfam; PF15269; zf-C2H2_7; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000472270};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 5..58
FT /note="Zinc finger protein 750-like zinc finger"
FT /evidence="ECO:0000259|Pfam:PF15269"
FT REGION 60..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 329..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 388..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..438
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..560
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..599
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 614 AA; 69124 MW; 0E79DC68D837C6EE CRC64;
MDTLQGRKPK KPHYIPRPAG KPFKYQCFQC PFTCNIKSHL FNHMKYNLCK NSISLVSQRM
EQTGKTQRTS QHNFPFNHKS KEPPLEAEAS KPTERVNDKV EQEEMGKGTR EKPESPIKEV
TKDVPEPICE TRDKNGDIDI EQNKISSAFS PVARTCESEA LSRSPHKDDQ SSSAIPQFYH
QMAPWVPPAS TAPLLPLISD YPSYMVSERS LHSLYTPYSH NQANTPAYQL TPRETQRPLV
PSPLVPPSTS LLHPYHYRYG HSIIPGPPLP YSLYQHPEFS MSLQRTRYLP LDVYSNRFYP
REYGGHLVPL HHPDSYSRLP EDRAFQEHNT VEKGTRQSPL AGCAASGSPD RPSTADITQR
IPVTLRHASH GESFPVSKSQ HVEPAATIAT ENLPKKSCGQ TQESMLQNKE RNEPQTTASA
RSSEISSEKE DEETEEEPAP LNLSKRDRAV SSNMTHHYPD CELHYDSESS QEEAPLNLCL
RVQSNNLALP NTTGSDTPER QTIINAEVCT IVPPREQEID PCDQRHSAAF ALCQLASSKD
IIIDSSIGQQ EMTEGQNSQS LPPPDKSPVK DTPDTPKQST LGQKRVNNRP PKHTTKRAKV
KEPARTQRKR SQNC
//
