ID A0A674NXA5_TAKRU Unreviewed; 424 AA.
AC A0A674NXA5;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 28-JAN-2026, entry version 21.
DE SubName: Full=HORMA domain containing 1 {ECO:0000313|Ensembl:ENSTRUP00000077571.1};
GN Name=hormad1 {ECO:0000313|Ensembl:ENSTRUP00000077571.1};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000077571.1, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000077571.1, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000077571.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSTRUP00000077571.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A674NXA5; -.
DR FunCoup; A0A674NXA5; 34.
DR Ensembl; ENSTRUT00000078782.1; ENSTRUP00000077571.1; ENSTRUG00000027948.1.
DR GeneTree; ENSGT00390000018130; -.
DR InParanoid; A0A674NXA5; -.
DR Proteomes; UP000005226; Chromosome 7.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR Gene3D; 3.30.900.10; HORMA domain; 1.
DR InterPro; IPR003511; HORMA_dom.
DR InterPro; IPR036570; HORMA_dom_sf.
DR InterPro; IPR051294; HORMA_MeioticProgression.
DR PANTHER; PTHR48225; HORMA DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR48225:SF3; HORMA DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF02301; HORMA; 1.
DR SUPFAM; SSF56019; The spindle assembly checkpoint protein mad2; 1.
DR PROSITE; PS50815; HORMA; 1.
PE 4: Predicted;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 24..222
FT /note="HORMA"
FT /evidence="ECO:0000259|PROSITE:PS50815"
FT REGION 286..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..301
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 424 AA; 47840 MW; D4B269B49B56B04B CRC64;
MACVQKMRTT QESQLLPNQV LSEQQSSLVI RKLLAIAVSG ITYLRGVFPE KAYGTKYVED
QKVMILREEG SCPGATQIVQ WLQGCFEAIQ LKYLRTVILS LFTDPALPQN VTEFYQFNIH
YTPEGIHMDF ESNKVSMSCS NTKKASILLV RKLYTLMQNL GPLPDSVSLN MKLAYYEEVT
PQDYQPPGFK EAEGDTLVFE KEPVKLTMGE VVTPYHTLKL GMATERHRLE QVEENVCVTE
KWVLRMTAET QSHVVEDEER SEMEKADTFN PDIQMICHEK IDSCEESTQV DPGPLETSSA
EVGQKRTRSG RIISTTVRER RDCEHASSDG CQIGLSVPNA RQPGNAVHTC DPEKTQIQRA
QRTVLTPRPH AGVTAPLRFS FVRFAAVFKA DVSFRLNSFH VCLRSILKFS FPFVSAGSRR
SRTG
//
