ID A0A6A1QKK1_BALPH Unreviewed; 327 AA.
AC A0A6A1QKK1;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 05-FEB-2025, entry version 11.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAB0406716.1};
DE Flags: Fragment;
GN ORFNames=E2I00_017838 {ECO:0000313|EMBL:KAB0406716.1};
OS Balaenoptera physalus (Fin whale) (Balaena physalus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=9770 {ECO:0000313|EMBL:KAB0406716.1, ECO:0000313|Proteomes:UP000437017};
RN [1] {ECO:0000313|EMBL:KAB0406716.1, ECO:0000313|Proteomes:UP000437017}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FinWhale-01 {ECO:0000313|EMBL:KAB0406716.1};
RX PubMed=31553763;
RA Westbury M.V., Petersen B., Lorenzen E.D.;
RT "Genomic analyses reveal an absence of contemporary introgressive admixture
RT between fin whales and blue whales, despite known hybrids.";
RL PLoS ONE 14:0-e0222004(2019).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the eukaryotic cobalamin transport proteins
CC family. {ECO:0000256|ARBA:ARBA00006449}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAB0406716.1}.
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DR EMBL; SGJD01000144; KAB0406716.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6A1QKK1; -.
DR OrthoDB; 6343110at2759; -.
DR Proteomes; UP000437017; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0015889; P:cobalamin transport; IEA:InterPro.
DR GO; GO:0006824; P:cobalt ion transport; IEA:UniProtKB-KW.
DR Gene3D; 1.50.10.20; -; 2.
DR Gene3D; 2.170.130.30; -; 1.
DR InterPro; IPR002157; Cbl-bd_prot.
DR InterPro; IPR051588; Cobalamin_Transport.
DR PANTHER; PTHR10559:SF15; COBALAMIN BINDING INTRINSIC FACTOR; 1.
DR PANTHER; PTHR10559; TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR; 1.
DR Pfam; PF01122; Cobalamin_bind; 1.
DR PROSITE; PS00468; COBALAMIN_BINDING; 1.
PE 3: Inferred from homology;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285, ECO:0000256|PIRSR:PIRSR602157-1};
KW Cobalt transport {ECO:0000256|ARBA:ARBA00022426};
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR602157-2};
KW Ion transport {ECO:0000256|ARBA:ARBA00022426};
KW Reference proteome {ECO:0000313|Proteomes:UP000437017};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transport {ECO:0000256|ARBA:ARBA00022426}.
FT BINDING 91
FT /ligand="cyanocob(III)alamin"
FT /ligand_id="ChEBI:CHEBI:17439"
FT /evidence="ECO:0000256|PIRSR:PIRSR602157-1"
FT BINDING 142
FT /ligand="cyanocob(III)alamin"
FT /ligand_id="ChEBI:CHEBI:17439"
FT /evidence="ECO:0000256|PIRSR:PIRSR602157-1"
FT BINDING 200
FT /ligand="cyanocob(III)alamin"
FT /ligand_id="ChEBI:CHEBI:17439"
FT /evidence="ECO:0000256|PIRSR:PIRSR602157-1"
FT BINDING 325
FT /ligand="cyanocob(III)alamin"
FT /ligand_id="ChEBI:CHEBI:17439"
FT /evidence="ECO:0000256|PIRSR:PIRSR602157-1"
FT DISULFID 63..102
FT /evidence="ECO:0000256|PIRSR:PIRSR602157-2"
FT NON_TER 327
FT /evidence="ECO:0000313|EMBL:KAB0406716.1"
SQ SEQUENCE 327 AA; 36206 MW; 6873BDA5DF5F940D CRC64;
MESSVVNSAF PNPSILIAMN LAGAYNLEAQ KLLTYKLMAS DTAGLNTHAS SFYGPSLAIL
ALCQNNPEKT LPIATRFAKS LLANSSPFNV DTGAMVTLAL TCMYHKIPVG SEDDYRVLFG
QVLKNTVENI SMRIQDNGII GNTYSTGLAM QSQTEKCLLL LIWFVNSIWD FSTCRVHREK
LYLGIKIKEG KFHNPMSIAQ ILPSLKGKTY LDVPHVSCSP GHEVQPTLPN PPSPVPTSAY
NITVKYTINN QLRGVERLFN ETINVSVKRG SVLLVVLEEA QRENPTFKFE TTMTSWGPMV
SSINNIAENV NHKTYWQFLS GKTPLNE
//
