ID A0A6A2ZMP9_HIBSY Unreviewed; 713 AA.
AC A0A6A2ZMP9;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 28-JAN-2026, entry version 18.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN ORFNames=F3Y22_tig00110828pilonHSYRG00066
GN {ECO:0000313|EMBL:KAE8692836.1};
OS Hibiscus syriacus (Rose of Sharon).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Hibiscus.
OX NCBI_TaxID=106335 {ECO:0000313|EMBL:KAE8692836.1, ECO:0000313|Proteomes:UP000436088};
RN [1] {ECO:0000313|EMBL:KAE8692836.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YM2019G1 {ECO:0000313|EMBL:KAE8692836.1};
RA Kim Y.-M.;
RT "Draft genome information of white flower Hibiscus syriacus.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAE8692836.1}.
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DR EMBL; VEPZ02001129; KAE8692836.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6A2ZMP9; -.
DR Proteomes; UP000436088; Unassembled WGS sequence.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016871; F:cycloartenol synthase activity; IEA:UniProtKB-ARBA.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR FunFam; 1.50.10.20:FF:000011; Terpene cyclase/mutase family member; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF20; LANOSTEROL SYNTHASE; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU362003};
KW Reference proteome {ECO:0000313|Proteomes:UP000436088};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 140..360
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 395..682
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 713 AA; 80802 MW; BBA72C845123F792 CRC64;
MWKLKFAEGG NPWLRSVNNH VGRQIWEFNP DLGSPEELME IEKARLDFTN DRLRKKHSSD
LLMRLQFSKE NPVPEVLPQV KVEEAKKVTE GMITNTLRRA INFHSSLQAH DGHWPGDYGG
PMFLMPGMII TLSITGQLNA NEDGGWGLHI EGPSTMFGSA LTYVTLRLLG EGPNDGEGAM
ERGRDWILNH GGATEITSWG KMWLSVLGAF EWSGNNPLPP EIWLLPYMLP LHPGRMWCHC
RMVYLPMSYL YGKRFVGPIT PTVLSLRKEL FTSPYHEIDW NQARNACAKE DLYYPHTLLQ
DILWASLHKI VEPILMCWAG KKLREKALQT VIEHIHYEDE NTRYICIGPV NKVLNMLCCW
VEDPNSEAFK LHLPRLYDYL WVAEDGMKMQ GYNGSQLWDT AFAVQAIISA NLTEEYSSTL
RKANMYLRNS QVQEDCQGDL NFWYRHISKG AWPFSTADHG WPISDCTAEG LKAVLLLSKI
SPEMVGEPLE ANRLYDAVNV ILSLQNADGG FATYELTRSY PWLELINPAE TFGDIVIDYP
YVECTSAAIQ ALTAFRKSHP GHRRHEVDQC IQNATKYIES IQASDGSWYG SWGVCFTYGT
WFGVKGLVAA GKSFNNSSSI QKACNFLLSK QLPSSGWGES YLSCQNKVYS NIEGNKPHVV
NTGWAMLALI DAGQVNCHSI TSPVESKIFK IKSSFVHPYM LVCKMFLIER NRT
//
