ID A0A6C2UA43_PONDE Unreviewed; 559 AA.
AC A0A6C2UA43;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 02-APR-2025, entry version 19.
DE SubName: Full=Aspartate/alanine antiporter {ECO:0000313|EMBL:VGO16865.1};
GN Name=aspT {ECO:0000313|EMBL:VGO16865.1};
GN ORFNames=PDESU_05457 {ECO:0000313|EMBL:VGO16865.1};
OS Pontiella desulfatans.
OC Bacteria; Pseudomonadati; Kiritimatiellota; Kiritimatiellia;
OC Kiritimatiellales; Pontiellaceae; Pontiella.
OX NCBI_TaxID=2750659 {ECO:0000313|EMBL:VGO16865.1, ECO:0000313|Proteomes:UP000366872};
RN [1] {ECO:0000313|EMBL:VGO16865.1, ECO:0000313|Proteomes:UP000366872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F1 {ECO:0000313|EMBL:VGO16865.1,
RC ECO:0000313|Proteomes:UP000366872};
RA Van Vliet M D.;
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC {ECO:0000256|ARBA:ARBA00009854}.
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DR EMBL; CAAHFG010000004; VGO16865.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6C2UA43; -.
DR Proteomes; UP000366872; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR050144; AAE_transporter.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR006512; YidE_YbjL.
DR NCBIfam; TIGR01625; YidE_YbjL_dupl; 2.
DR PANTHER; PTHR30445; K(+)_H(+) ANTIPORTER SUBUNIT KHTT; 1.
DR PANTHER; PTHR30445:SF3; TRANSPORT PROTEIN YIDE-RELATED; 1.
DR Pfam; PF06826; Asp-Al_Ex; 2.
DR Pfam; PF02080; TrkA_C; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR PROSITE; PS51202; RCK_C; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000366872};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 506..525
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 537..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 290..373
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 559 AA; 58546 MW; C8B31DE108C96985 CRC64;
MGIRGYSPRL HHLTRKTDAM SLEALHNLLL NQPLIVLFAL IATGLLLGGV KFKGINLGSS
GVLFSALLAG HLGYSIPSGV GTLGLVLFVY CVGIGAGDRF FASLVREGTA LAKLAVLIVA
LGAAMTWAGA TLLDIPTGLA AGIFAGSLTS TPALAAATEG MAMAAKGGAD AVSIGYGIAY
PFGVIGVVLF VQILPRILKL DLDSIADKPD TTCGNRVENV LVEVNNPNLY GQRISESGVT
NFNACQICRI YSGGSLVPLK YDDQFEENQI LLLVGRSCEL KIAIDMIGKR SDRKLPQDIE
NERQQLVVTS TAFIGQKLGD VAPLRNYGVV IARITRLGLT FVPNANTVIE RHDHFTCVGR
ADDLKKFSVA AGHRSSAVDA TCLLSLSVGL TFGILLGMLP FGLPGGTPVT LGLAGGPLFV
ALILGHFGKI GPIVGFIPRQ TRLLLQELGL VFFLANAGVR GGGALVSTLQ EHGFMLFALG
VGVSVLPLIV AWPVAIRHFK MNPLQALGGI CGGMTSTPAL GAITAKTDSQ TPVISYVSAY
PVALIFMIII SKVLIKLIG
//
