ID A0A6G0XJH5_9STRA Unreviewed; 551 AA.
AC A0A6G0XJH5;
DT 12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT 12-AUG-2020, sequence version 1.
DT 28-JAN-2026, entry version 13.
DE RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
GN ORFNames=Ae201684_004152 {ECO:0000313|EMBL:KAF0740416.1};
OS Aphanomyces euteiches.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniomycetes;
OC Saprolegniales; Verrucalvaceae; Aphanomyces.
OX NCBI_TaxID=100861 {ECO:0000313|EMBL:KAF0740416.1, ECO:0000313|Proteomes:UP000481153};
RN [1] {ECO:0000313|EMBL:KAF0740416.1, ECO:0000313|Proteomes:UP000481153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 201684 {ECO:0000313|EMBL:KAF0740416.1,
RC ECO:0000313|Proteomes:UP000481153};
RA Gaulin E.;
RT "Genomics analysis of Aphanomyces spp. identifies a new class of oomycete
RT effector associated with host adaptation.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|RuleBase:RU361203};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC acid phosphatase family. {ECO:0000256|RuleBase:RU361203}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF0740416.1}.
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DR EMBL; VJMJ01000052; KAF0740416.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6G0XJH5; -.
DR VEuPathDB; FungiDB:AeMF1_005191; -.
DR Proteomes; UP000481153; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00839; MPP_PAPs; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041792; MPP_PAP.
DR InterPro; IPR025733; PAPs_C.
DR InterPro; IPR015914; PAPs_N.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR PANTHER; PTHR45778:SF7; PURPLE ACID PHOSPHATASE; 1.
DR PANTHER; PTHR45778; PURPLE ACID PHOSPHATASE-RELATED; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF14008; Metallophos_C; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|RuleBase:RU361203};
KW Reference proteome {ECO:0000313|Proteomes:UP000481153};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361203}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT CHAIN 21..551
FT /note="Purple acid phosphatase"
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT /id="PRO_5026372323"
FT DOMAIN 131..236
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
FT DOMAIN 248..469
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 484..544
FT /note="Purple acid phosphatase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14008"
SQ SEQUENCE 551 AA; 61778 MW; EE9216C971FEC7A0 CRC64;
MTARMVATLA MAMLLAVATA RESPWRYDET PKCFEMYASP EKLDLGGDVV VSWTGVHSHP
SDYLTISCGP TQGLNDYIKR VNVTTSTSSV RFEDLHMLRC VYTASYFHFN GSAFHLLGQV
SIPMKTSINS PQQGHVAFNE HLDQMVVMYN SASNWTPSVK YGRDPNLAHA ELRHGTSTTY
NATDMCHEPA TIVAQQWFRD PGFMHTIVID NLELATTYFY QFGNDHDGWS AAYSFTSRPP
ANSTAPVKFI AYGDMGVDNA PAAWSTAMRV FQDIENGYDG FLLHFGDISY ARGIGLQWDK
FMYIIEPIAT RLPYMVSLGN HEYDYIGGGE HDPSHPMTPN GFHPDWGNYG VDSLGECGVP
TVHRFRGPAN GHGLFWYSFD YAFLHVVQLS SEHDYRPGSL QYKWLAADLA AVDRSKQPWI
VLTAHRMMYT TQLDEVEDYR VSVHFRAALE PLLHQFRVNL VLVGHQHSYE RSCPVYNGTC
VDQGTVHIIA GSAGAELEKS GFSPKLGPWS VANVNAWGYL RLEASLDALH VAFVRNDNGN
IYDETTIARW T
//
