ID A0A6I6MU01_9CAUL Unreviewed; 275 AA.
AC A0A6I6MU01;
DT 12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT 12-AUG-2020, sequence version 1.
DT 02-APR-2025, entry version 19.
DE RecName: Full=Serine acetyltransferase {ECO:0000256|ARBA:ARBA00018522};
DE EC=2.3.1.30 {ECO:0000256|ARBA:ARBA00013266};
GN Name=cysE {ECO:0000313|EMBL:QGZ94643.1};
GN ORFNames=DSM104635_01464 {ECO:0000313|EMBL:QGZ94643.1};
OS Terricaulis silvestris.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Caulobacterales; Caulobacteraceae; Terricaulis.
OX NCBI_TaxID=2686094 {ECO:0000313|EMBL:QGZ94643.1, ECO:0000313|Proteomes:UP000431269};
RN [1] {ECO:0000313|Proteomes:UP000431269}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0127_4 {ECO:0000313|Proteomes:UP000431269};
RA Vieira S., Riedel T., Sproer C., Pascual J., Boedeker C., Overmann J.;
RT "Complete genome of Terracaulis silvestris 0127_4.";
RL Submitted (DEC-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-serine + acetyl-CoA = O-acetyl-L-serine + CoA;
CC Xref=Rhea:RHEA:24560, ChEBI:CHEBI:33384, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57288, ChEBI:CHEBI:58340; EC=2.3.1.30;
CC Evidence={ECO:0000256|ARBA:ARBA00049486};
CC -!- PATHWAY: Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine
CC from L-serine: step 1/2. {ECO:0000256|ARBA:ARBA00004876}.
CC -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC {ECO:0000256|ARBA:ARBA00007274}.
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DR EMBL; CP047045; QGZ94643.1; -; Genomic_DNA.
DR RefSeq; WP_158765566.1; NZ_CP047045.1.
DR AlphaFoldDB; A0A6I6MU01; -.
DR KEGG; tsv:DSM104635_01464; -.
DR UniPathway; UPA00136; UER00199.
DR Proteomes; UP000431269; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0009001; F:serine O-acetyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR CDD; cd03354; LbH_SAT; 1.
DR FunFam; 2.160.10.10:FF:000002; Serine acetyltransferase; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR Gene3D; 1.10.3130.10; serine acetyltransferase, domain 1; 1.
DR InterPro; IPR001451; Hexapep.
DR InterPro; IPR018357; Hexapep_transf_CS.
DR InterPro; IPR045304; LbH_SAT.
DR InterPro; IPR010493; Ser_AcTrfase_N.
DR InterPro; IPR042122; Ser_AcTrfase_N_sf.
DR InterPro; IPR005881; Ser_O-AcTrfase.
DR InterPro; IPR053376; Serine_acetyltransferase.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR NCBIfam; TIGR01172; cysE; 1.
DR NCBIfam; NF041874; EPS_EpsC; 1.
DR PANTHER; PTHR42811; SERINE ACETYLTRANSFERASE; 1.
DR Pfam; PF00132; Hexapep; 1.
DR Pfam; PF06426; SATase_N; 1.
DR SMART; SM00971; SATase_N; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
DR PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:QGZ94643.1};
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Reference proteome {ECO:0000313|Proteomes:UP000431269};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:QGZ94643.1}.
FT DOMAIN 15..119
FT /note="Serine acetyltransferase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00971"
SQ SEQUENCE 275 AA; 29726 MW; 6E95A8C7E18201B6 CRC64;
MAESQMRLFE ASGGVWAQLR VEAMQAAAEE PLLASYLHAS ILHHDRIEDA LSYHLAQKLG
HGDLPALQLR EVIREAYASD PAIGAMALRD MRVVRERDPA CTTYLQPFLY FKGYGGLQSF
RIAHWLWTQD RQILAYHLQS RVSELFSVDI HPAATIGAGV FIDHAHGIVI GETAVVEDDV
SMLHSVTLGG TGNAGGDRHP KIRRGVLIGA GAKVLGNIEV GEDARIAAGS VVLENVAPRC
TVAGIPARPV GGECCEDTIP AVAMNQRFES DKSQS
//
