ID   A0A6I8T920_AEDAE        Unreviewed;       647 AA.
AC   A0A6I8T920;
DT   12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT   12-AUG-2020, sequence version 1.
DT   02-APR-2025, entry version 16.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:AAEL003996-PD};
GN   Name=5563917 {ECO:0000313|EnsemblMetazoa:AAEL003996-PD};
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159 {ECO:0000313|EnsemblMetazoa:AAEL003996-PD, ECO:0000313|Proteomes:UP000008820};
RN   [1] {ECO:0000313|EnsemblMetazoa:AAEL003996-PD, ECO:0000313|Proteomes:UP000008820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL003996-PD,
RC   ECO:0000313|Proteomes:UP000008820};
RG   Aedes aegypti Genome Working Group (AGWG);
RA   Matthews B.J.;
RT   "Aedes aegypti genome working group (AGWG) sequencing and assembly.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AAEL003996-PD}
RP   IDENTIFICATION.
RC   STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL003996-PD};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   AlphaFoldDB; A0A6I8T920; -.
DR   EnsemblMetazoa; AAEL003996-RD; AAEL003996-PD; AAEL003996.
DR   OrthoDB; 6270329at2759; -.
DR   Proteomes; UP000008820; Chromosome 3.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:TreeGrafter.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:TreeGrafter.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR052443; E3_ubiq-ligase_RNF220-like.
DR   InterPro; IPR031824; RNF220_mid.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR13459; E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1; 1.
DR   PANTHER; PTHR13459:SF1; E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1; 1.
DR   Pfam; PF15926; RNF220; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022771};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008820};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   REGION          125..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          344..415
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          512..570
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..145
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        158..173
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        344..363
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        364..376
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        377..394
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        395..407
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        532..566
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   647 AA;  71465 MW;  B32E42822338FD15 CRC64;
     MDNPSYGSSH MSSPALVVFS QAANGLSDAL RIQRPFNSHL PDAKDLHHLS LMSGYGAHLL
     HGFQPHFLHP LNPAVSTANG TSPFGGGGAF VKPFPSNLPL PSAFAPPKCL GFGIDQGLLF
     GSSSGSESFR TSDSSSPACA SLSPPAKDES MEGQTSEEGD RDRDRICSPE RSPETPGFRQ
     LLSLFGPKNH FLSYVDDQNK TIRRIGPPKK TFVGTPPPNS CPICGIQLAP SDLETHFSAE
     LTRLTKMSSA AERLELRRTL SVDMHAMQNT LQGRTSRWET FKNIRNKRQD RLRGKLRKRK
     FDGEDGFGLQ LGNLNCQSCP VCHGRLQRTQ EEIAQHIEDC VRKQQQQHQQ QHHQQQQSGQ
     SSAQDEDETV DVESYGDETS NGAINMTSNV IHHTNNSLHN NNNNNNNTPM KPDPPMTKLP
     PMEESAITSL SSIVPHWDRK NRLNLPLNCT ATSDNSITRV TPTSSDQRID VDYEQDHDHS
     QDMVTDHDEE VIVDNTDDEE CIKRPRQTGL GSHVCNGNPG LGVARDDKNS TEEATSSVEI
     DSATDSMTIR TAGTTPNSDS YVSTSEPAEP SSKAQVLEEL KARIRELEGS PHYKCFICKE
     KCKALIISKI CGHYLCEECW ITETDSSKTC PRCKIITANS DFRKIYA
//