ID A0A6I9HFR7_GEOFO Unreviewed; 796 AA.
AC A0A6I9HFR7;
DT 07-OCT-2020, integrated into UniProtKB/TrEMBL.
DT 07-OCT-2020, sequence version 1.
DT 28-JAN-2026, entry version 25.
DE SubName: Full=Protein ELFN1 {ECO:0000313|RefSeq:XP_005420411.1, ECO:0000313|RefSeq:XP_030912438.1};
GN Name=ELFN1 {ECO:0000313|RefSeq:XP_005420411.1,
GN ECO:0000313|RefSeq:XP_030912438.1};
OS Geospiza fortis (Medium ground-finch).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Thraupidae; Geospiza.
OX NCBI_TaxID=48883 {ECO:0000313|Proteomes:UP000504602, ECO:0000313|RefSeq:XP_005420411.1};
RN [1] {ECO:0000313|RefSeq:XP_005420411.1, ECO:0000313|RefSeq:XP_030912438.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (APR-2025) to UniProtKB.
CC -!- SUBUNIT: Interacts with PPP1CA. {ECO:0000256|ARBA:ARBA00065735}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR RefSeq; XP_005420411.1; XM_005420354.2.
DR RefSeq; XP_030912438.1; XM_031056578.1.
DR AlphaFoldDB; A0A6I9HFR7; -.
DR GeneID; 102043781; -.
DR KEGG; gfr:102043781; -.
DR CTD; 392617; -.
DR GeneTree; ENSGT00940000161391; -.
DR OrthoDB; 676979at2759; -.
DR Proteomes; UP000504602; Unplaced.
DR GO; GO:0043679; C:axon terminus; IEA:Ensembl.
DR GO; GO:0030425; C:dendrite; IEA:Ensembl.
DR GO; GO:0060076; C:excitatory synapse; IEA:Ensembl.
DR GO; GO:0098978; C:glutamatergic synapse; IEA:Ensembl.
DR GO; GO:0098839; C:postsynaptic density membrane; IEA:Ensembl.
DR GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR GO; GO:0007268; P:chemical synaptic transmission; IEA:Ensembl.
DR GO; GO:0045184; P:establishment of protein localization; IEA:Ensembl.
DR GO; GO:0007416; P:synapse assembly; IEA:Ensembl.
DR GO; GO:0099560; P:synaptic membrane adhesion; IEA:Ensembl.
DR GO; GO:0007601; P:visual perception; IEA:Ensembl.
DR FunFam; 3.80.10.10:FF:000047; protein phosphatase 1 regulatory subunit 29; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR055106; ELFN_Fn3.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR050541; LRR_TM_domain-containing.
DR PANTHER; PTHR24369; ANTIGEN BSP, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR24369:SF204; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 29-RELATED; 1.
DR Pfam; PF22986; Fn3_ELFN; 1.
DR Pfam; PF13855; LRR_8; 2.
DR SMART; SM00369; LRR_TYP; 4.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein phosphatase inhibitor {ECO:0000256|ARBA:ARBA00023272};
KW Reference proteome {ECO:0000313|Proteomes:UP000504602};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..796
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5044634668"
FT TRANSMEM 407..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 192..239
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT REGION 609..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..633
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..649
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 796 AA; 89645 MW; B87565E2B33E9190 CRC64;
MAGRRWAATS ALCMCVAAVS LLHAGGVRAD CWLIEGDKGF VWLAICSQNQ PPYESIPQQI
NSTIVDLRLN DNKIKSVQYA SLSRFGNLTY LNLTKNEISY IEDGAFSGQF NLQVLQLGYN
RLRNLTEGIL RGLGKLEYLY LQANLIETVT PNAFWECPNI VNIDLSMNRI QRLDSNTFRG
LNKLSVCELY SNPFYCSCEL LGFLQWLEAF TNMTRTYDRM QCDSPPDYMG YYLLGQGRTG
YRNALSMLSS LCTGGSYTVI PRFIPPRYQV TTVPSESPCS EEECSSGDGT TPQFSLFTPI
GETEVRPNIQ VKHLNHNSAV LTVQIPYPFS KMYILSQFEN GFSSMITKLR KKEENITVSN
LVAQRDYTYC VVSVHQYSKY NHTCVTITPT RPNRKEPVPT PSTATHYIMT ILGCLFGMVI
VLGVVYYCLR KRRQQEEKHK KAAGSMKKTI IELKYGPEME TTSITQLSQG QILGGETVTR
IPYLPSAGEV EQYKLIESSE TPKATKGNYM EVRTGEQPER RDCELSLPPD TQGSVAEIST
IAKEVDKVNQ IINNCIDALK SESTSFQGVK SGAVSTVEPQ LVLLSEQIPS KHGFLSPVYK
ESYNHPLQRP HSMEAAPKRS STSSSGSIRS PRSYRSEGSG HKSEAKYIEK TSPTTDTILT
VTPAAAILRA EAEKIRQYSE HRHSYPSSHP GEQHDSMGGR KPSILEPLTR PRPRDLAYSQ
LSPQYHNLSY TSSPEYTCKP SHSIWERFKL NRKRHKDEEE YMAAGHALRK KVQFAKDEDL
HDILDYWKGV SAQQKS
//
