ID   A0A6I9I1T3_VICPA        Unreviewed;       684 AA.
AC   A0A6I9I1T3;
DT   07-OCT-2020, integrated into UniProtKB/TrEMBL.
DT   07-OCT-2020, sequence version 1.
DT   08-OCT-2025, entry version 23.
DE   RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN   Name=ZNF750 {ECO:0000313|RefSeq:XP_006199539.1,
GN   ECO:0000313|RefSeq:XP_072796052.1, ECO:0000313|RefSeq:XP_072796053.1};
OS   Vicugna pacos (Alpaca) (Lama pacos).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Vicugna.
OX   NCBI_TaxID=30538 {ECO:0000313|Proteomes:UP001652581, ECO:0000313|RefSeq:XP_006199539.1};
RN   [1] {ECO:0000313|RefSeq:XP_006199539.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_006199539.1};
RG   RefSeq;
RL   Submitted (APR-2025) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_006199539.1; XM_006199477.3.
DR   RefSeq; XP_072796052.1; XM_072939951.1.
DR   RefSeq; XP_072796053.1; XM_072939952.1.
DR   AlphaFoldDB; A0A6I9I1T3; -.
DR   FunCoup; A0A6I9I1T3; 56.
DR   GeneID; 102533884; -.
DR   KEGG; vpc:102533884; -.
DR   CTD; 79755; -.
DR   InParanoid; A0A6I9I1T3; -.
DR   OrthoDB; 8933073at2759; -.
DR   Proteomes; UP001652581; Chromosome 16.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR   GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR   InterPro; IPR039363; ZNF750.
DR   InterPro; IPR039064; ZNF750_Znf.
DR   PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR   PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR   Pfam; PF15269; zf-C2H2_7; 1.
PE   4: Predicted;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP001652581};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          6..57
FT                   /note="Zinc finger protein 750-like zinc finger"
FT                   /evidence="ECO:0000259|Pfam:PF15269"
FT   REGION          60..164
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          358..601
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          614..684
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        73..86
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        98..115
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        142..159
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        375..399
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        418..428
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        456..467
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        568..581
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        629..645
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   684 AA;  73379 MW;  4B474FB22C18B58E CRC64;
     MSLLKERKPK KPHYIPRPPG KPFRYKCFQC PFTCNEKSHL FNHMKYGLCK NSITLVSEQD
     RAPRCPKPRS SDPGPAGQPG PTATPASSKP GLGALAHLDT KPQHGPPTDD AKENPDLQAR
     GPHRGAGQRP ALHKEEAPPS PAAEATTRTP PATEGATRPS AFVPIGEHRL KGQELTEAPE
     ALAPPHPAAK AASFHAKSAF HAPGYPWKAG SPFLPPEFPH KIPSTKGFGA TAPYMHPAVP
     EYPPHFYTEH GLATIYSPYL LAGNPAECDS PLLSVYGAQD QRHFLPHPGP LPKHLNPAPS
     TYDHYRVFQQ FHSNLPIPYG FYRPESAFSS YGLRLPPIAG ISRDQSPHLL EEATLVYPTS
     SPSKIHSSSS HRKHTEFEKE GPTREAKDPS RDGQRDPEGT KMSPRAGSAA TGSPGRPSPT
     NFTQTRQPCS GLCGLPDQPA SSGPGRLQAP QQSPVAFPPE CPHPQPPESR DKSPESLEAG
     SAEAPAQTGH TSPGPDPTPC SPEDSSRTAP LNLSKKPEVE LTATHTPAYG DFTEPQDVPL
     NLSVKDPCNA LTPRPSFHSP SRGPEPTTAP TMRTEPASSG DASPGEAPDT QAVDSEEQKQ
     TAAVALCQLA AYSAGTSRPG EGEPTAQELS HHTPESQEAP CDLRPKGQKR TSPRDAGKSQ
     QGAKRAKPSD TTRVFTLRKR TRVS
//