ID A0A6I9W2W9_9HYME Unreviewed; 310 AA.
AC A0A6I9W2W9;
DT 07-OCT-2020, integrated into UniProtKB/TrEMBL.
DT 07-OCT-2020, sequence version 1.
DT 18-JUN-2025, entry version 22.
DE RecName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000256|ARBA:ARBA00015711};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
DE AltName: Full=RING finger protein 41 {ECO:0000256|ARBA:ARBA00030556};
DE AltName: Full=RING-type E3 ubiquitin transferase NRDP1 {ECO:0000256|ARBA:ARBA00031762};
GN Name=LOC105426528 {ECO:0000313|RefSeq:XP_011636095.1};
OS Pogonomyrmex barbatus (red harvester ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Pogonomyrmex.
OX NCBI_TaxID=144034 {ECO:0000313|Proteomes:UP000504615, ECO:0000313|RefSeq:XP_011636095.1};
RN [1] {ECO:0000313|RefSeq:XP_011636095.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (MAR-2025) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_011636095.1; XM_011637793.1.
DR AlphaFoldDB; A0A6I9W2W9; -.
DR EnsemblMetazoa; XM_011637793.1; XP_011636095.1; LOC105426528.
DR GeneID; 105426528; -.
DR CTD; 39735; -.
DR OrthoDB; 1630758at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000504615; Unplaced.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0043122; P:regulation of canonical NF-kappaB signal transduction; IEA:TreeGrafter.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProtKB-ARBA.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR015036; NRDP1.
DR InterPro; IPR037255; NRDP1_C.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR10131:SF157; RECEPTOR-ASSOCIATED FACTOR, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR10131; TNF RECEPTOR ASSOCIATED FACTOR; 1.
DR Pfam; PF08941; USP8_interact; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SUPFAM; SSF160088; NRDP1 C-terminal domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000504615};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 29..52
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT COILED 130..164
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 310 AA; 36023 MW; E9A1F1FE0C1F14EE CRC64;
MFWRPRGSCS VVAAYEDWQV SNVLQAPVCE HAFCRTCINE WINRQPTCPL DRTPITSAQL
RAVPRILRNL LARLCIKCDN IVYGCNAVIK LDCLAIHLEQ CEYNPKRPML CEQGCSLIIP
KNELKDHNCV RELRNLIQSQ QQKLADMKRE LGEQQLQINE HKREIHLLKD FMRALRVSNP
AMRAIADQME RDDVVRWSAT LPRARVTRWG GMISTPDELL QTMIKRTLSE YNCPPHVIDE
LMENCHERKW PPGLNSLETR QNSRRQYDNY VCKRVPGKQA VLVLHCDNMH MPEDMMVEPG
LVMIFAHGIE
//
