ID   A0A6I9YEW8_9SAUR        Unreviewed;       736 AA.
AC   A0A6I9YEW8;
DT   07-OCT-2020, integrated into UniProtKB/TrEMBL.
DT   07-OCT-2020, sequence version 1.
DT   28-JAN-2026, entry version 23.
DE   SubName: Full=Zinc finger protein 598-like {ECO:0000313|RefSeq:XP_013922712.1};
GN   Name=LOC106549546 {ECO:0000313|RefSeq:XP_013922712.1};
OS   Thamnophis sirtalis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Colubridae; Natricinae; Thamnophis.
OX   NCBI_TaxID=35019 {ECO:0000313|Proteomes:UP000504617, ECO:0000313|RefSeq:XP_013922712.1};
RN   [1] {ECO:0000313|RefSeq:XP_013922712.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (AUG-2025) to UniProtKB.
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DR   RefSeq; XP_013922712.1; XM_014067237.1.
DR   AlphaFoldDB; A0A6I9YEW8; -.
DR   GeneID; 106549546; -.
DR   KEGG; tsr:106549546; -.
DR   OrthoDB; 3838338at2759; -.
DR   Proteomes; UP000504617; Unplaced.
DR   GO; GO:0043022; F:ribosome binding; IEA:TreeGrafter.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:TreeGrafter.
DR   GO; GO:0072344; P:rescue of stalled ribosome; IEA:InterPro.
DR   InterPro; IPR057634; PAH_ZNF598/HEL2.
DR   InterPro; IPR044288; ZNF598/HEL2.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   InterPro; IPR059042; Znf_C2H2_ZNF598.
DR   PANTHER; PTHR22938:SF0; E3 UBIQUITIN-PROTEIN LIGASE ZNF598; 1.
DR   PANTHER; PTHR22938; ZINC FINGER PROTEIN 598; 1.
DR   Pfam; PF23202; PAH_ZNF598; 1.
DR   Pfam; PF23208; zf_C2H2_ZNF598; 1.
DR   SMART; SM00355; ZnF_C2H2; 4.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000504617}.
FT   DOMAIN          35..56
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS00028"
FT   REGION          133..276
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          336..396
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          437..546
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          667..688
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        161..177
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        192..201
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        202..228
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..249
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        265..276
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        336..348
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        385..396
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        532..546
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        667..677
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|RefSeq:XP_013922712.1"
SQ   SEQUENCE   736 AA;  81617 MW;  78291E49466C0239 CRC64;
     KIFTYERKWY SRKDLARHRI HGDPDDTSHR GHPLCKFCDE RYLDNDELLK HLRRDHYFCH
     FCDSDGAQEY YSDYEYLREH FREKHFLCEE GRCSTEQFTH AFRTEIDYKA HKTACHSKNR
     AEARQNRQID LQFNYAPRHQ RRNEGVVSGE DYDEVDRYNR QMRGSRSGSR GGQQNRRGSW
     RYKREEEDRD VAAAVRASVA AKRQEEKNRV EDKGDSCRPK KEDAKDPEPT VSKRGVKPSS
     EEPVPKEAVP KAALSQDDFP AIGSPNMNSV PSSSQLAPVK LDEEDFPRLS FSSAPPVVSA
     SLPLSYMATA QKTGFQEEDF PALVSKVRPS SKTVSTLASA WSGGSSKNMA RAMTATASQP
     ARKGPPPGSS KASKKSKVAI PGNFQDGSGS VSTQEIRSAP TMVDVSSLLA ASNSQTFAKV
     GKKKKVGTEK LRTVLQEVPA APHSLEKVDD AEQSSPVTAG PDLLSTSATL VNGHSEKPPL
     PCRAPKEPPG LKKPSGGGQC LLPQEDFPAL GNTGPPRMPP PPGFNSVVLL NSPPPPPGLS
     VPPSKPPPGF TPIPTTGTSE NAPASVKEPK LCQGPYLILE NFQQRNIQLI QSIREFLQED
     ESQFNKFKMY SGQFRQGLIS AEQYYKSCQE LLGENFNKIF NELLVLLPDT AKQQELLSAY
     QDLKVKAPAG SSSPSSTRSK KNRKGVWHTE PPSDLDCCVC PTCQQVLTQQ DLVSHQALHL
     EEEEFPSLQA ISRIIS
//