ID A0A6J0MAR7_RAPSA Unreviewed; 220 AA.
AC A0A6J0MAR7;
DT 07-OCT-2020, integrated into UniProtKB/TrEMBL.
DT 07-OCT-2020, sequence version 1.
DT 28-JAN-2026, entry version 23.
DE RecName: Full=Calcyclin-binding protein {ECO:0000256|ARBA:ARBA00015702};
GN Name=LOC108840307 {ECO:0000313|RefSeq:XP_018468646.1};
OS Raphanus sativus (Radish) (Raphanus raphanistrum var. sativus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus.
OX NCBI_TaxID=3726 {ECO:0000313|Proteomes:UP000504610, ECO:0000313|RefSeq:XP_018468646.1};
RN [1] {ECO:0000313|Proteomes:UP000504610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. WK10039 {ECO:0000313|Proteomes:UP000504610};
RX PubMed=30722041;
RA Yu H.J., Baek S., Lee Y.J., Cho A., Mun J.H.;
RT "The radish genome database (RadishGD): an integrated information resource
RT for radish genomics.";
RL Database 2019:5306501-5306501(2019).
RN [2] {ECO:0000313|RefSeq:XP_018468646.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_018468646.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- FUNCTION: May be involved in calcium-dependent ubiquitination and
CC subsequent proteasomal degradation of target proteins. Probably serves
CC as a molecular bridge in ubiquitin E3 complexes. Participates in the
CC ubiquitin-mediated degradation of beta-catenin (CTNNB1).
CC {ECO:0000256|ARBA:ARBA00025145}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_018468646.1; XM_018613144.2.
DR AlphaFoldDB; A0A6J0MAR7; -.
DR GeneID; 108840307; -.
DR KEGG; rsz:108840307; -.
DR OrthoDB; 164025at2759; -.
DR Proteomes; UP000504610; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0044548; F:S100 protein binding; IEA:InterPro.
DR GO; GO:0015631; F:tubulin binding; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006950; P:response to stress; IEA:UniProtKB-ARBA.
DR CDD; cd06468; p23_CacyBP; 1.
DR FunFam; 2.60.40.790:FF:000040; Calcyclin binding protein; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR InterPro; IPR037201; CacyBP_N.
DR InterPro; IPR037893; CS_CacyBP.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR007699; SGS_dom.
DR InterPro; IPR015120; Siah-Interact_N.
DR PANTHER; PTHR47686:SF1; CALCYCLIN-BINDING PROTEIN; 1.
DR PANTHER; PTHR47686; SGS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF04969; CS; 1.
DR Pfam; PF09032; Siah-Interact_N; 1.
DR SUPFAM; SSF140106; Calcyclin-binding protein-like; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR PROSITE; PS51203; CS; 1.
DR PROSITE; PS51048; SGS; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000504610};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 72..162
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT DOMAIN 147..220
FT /note="SGS"
FT /evidence="ECO:0000259|PROSITE:PS51048"
SQ SEQUENCE 220 AA; 24774 MW; C4570EEE30AA62E5 CRC64;
MAEEVGLDLE ELRQLQNIAK RTRVLNLISS EICNLEKLRE SASASNVKPE LEPVPAPVSS
SVKPVSPALN YVTLGTFSWD QDNEKVKVYI SLEGVDENKV EAEFKPMSLD VKIHDVQGKN
YRCAIPKLHK EIVPEKCKVL VKPKRIVITM FKSSRGNWMD IHYKEDKIKP SLEKEKDPMA
GIMDLMKNMY EGGDEEMKKT IAKAWTDARS GKAGDSLKGL
//
