ID A0A6J2LJG6_9CHIR Unreviewed; 563 AA.
AC A0A6J2LJG6;
DT 07-OCT-2020, integrated into UniProtKB/TrEMBL.
DT 07-OCT-2020, sequence version 1.
DT 28-JAN-2026, entry version 24.
DE SubName: Full=Glucocorticoid modulatory element binding protein 1 {ECO:0000313|EMBL:KAF6108932.1};
DE SubName: Full=Glucocorticoid modulatory element-binding protein 1 isoform X2 {ECO:0000313|RefSeq:XP_028367476.1};
GN Name=GMEB1 {ECO:0000313|RefSeq:XP_028367476.1};
GN ORFNames=HJG60_005670 {ECO:0000313|EMBL:KAF6108932.1};
OS Phyllostomus discolor (pale spear-nosed bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae;
OC Phyllostominae; Phyllostomus.
OX NCBI_TaxID=89673 {ECO:0000313|Proteomes:UP000504628, ECO:0000313|RefSeq:XP_028367476.1};
RN [1] {ECO:0000313|EMBL:KAF6108932.1, ECO:0000313|Proteomes:UP000664940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bat1K_MPI-CBG_1 {ECO:0000313|EMBL:KAF6108932.1};
RX PubMed=32699395;
RA Jebb D., Huang Z., Pippel M., Hughes G.M., Lavrichenko K., Devanna P.,
RA Winkler S., Jermiin L.S., Skirmuntt E.C., Katzourakis A., Burkitt-Gray L.,
RA Ray D.A., Sullivan K.A.M., Roscito J.G., Kirilenko B.M., Davalos L.M.,
RA Corthals A.P., Power M.L., Jones G., Ransome R.D., Dechmann D.K.N.,
RA Locatelli A.G., Puechmaille S.J., Fedrigo O., Jarvis E.D., Hiller M.,
RA Vernes S.C., Myers E.W., Teeling E.C.;
RT "Six reference-quality genomes reveal evolution of bat adaptations.";
RL Nature 583:578-584(2020).
RN [2] {ECO:0000313|RefSeq:XP_028367476.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_028367476.1};
RG RefSeq;
RL Submitted (APR-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; JABVXQ010000005; KAF6108932.1; -; Genomic_DNA.
DR RefSeq; XP_028367476.1; XM_028511675.2.
DR AlphaFoldDB; A0A6J2LJG6; -.
DR GeneID; 114496353; -.
DR KEGG; pdic:114496353; -.
DR CTD; 10691; -.
DR Proteomes; UP000504628; Chromosome 5.
DR Proteomes; UP000664940; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:TreeGrafter.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:TreeGrafter.
DR FunFam; 3.10.390.10:FF:000003; glucocorticoid modulatory element-binding protein 1 isoform X2; 1.
DR Gene3D; 3.10.390.10; SAND domain-like; 1.
DR InterPro; IPR059099; GMEB1/2/Spe-44_dom.
DR InterPro; IPR010919; SAND-like_dom_sf.
DR InterPro; IPR000770; SAND_dom.
DR PANTHER; PTHR10417; GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN; 1.
DR PANTHER; PTHR10417:SF3; GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 1; 1.
DR Pfam; PF01342; SAND; 1.
DR Pfam; PF25892; Spe-44; 1.
DR SMART; SM00258; SAND; 1.
DR SUPFAM; SSF63763; SAND domain-like; 1.
DR PROSITE; PS50864; SAND; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000504628};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 72..156
FT /note="SAND"
FT /evidence="ECO:0000259|PROSITE:PS50864"
FT REGION 360..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 304..349
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 563 AA; 61428 MW; 9953308AECC7ED0E CRC64;
MANAEVSVPV GDVVVVPTEG NEGENPEDTK TQVILQLQPV QQGIYEAGSE NNTAVVAVET
HTIHKIEEGI DASTIEANED MEIAYPITCG ESKAILLWKK FVCPGINVKC VKFNDQLISP
KHFVHLAGKS TLKDWKRAIR LGGIMLRKMM DSGQIDFYQH DKVCSNTCRS TKFDLLISSA
RAPVPGQQTS VVQTPTSADG NITQIAISEE SMEEAGLEWN SALTAAVTMA TEEGVKKDSE
EISEDTLMFW KGIADVGLME EVVCNIQKEI EELLRGVQQR LIQAPFQVTD AAVLNNVAHT
FGLMDTVKKV LDNRRNQIEQ GEEQFLYTLT DLERQLEEQK KQAQDHRLKS QTVQNVVLMP
VSTPKPPKRP RLQRPASTTV LSPSPPVQQP QFTVISPITI TPVGQSFSMG NIPVATLSQG
SSPVTVHTLP SGPQLFRYAT VVSSAKSSSP DTVTIHPSSS LTLLSSTAMQ DGSTLGNMTT
MVSPVELVAM ESGLTSTIQA VESTSEDGQT IIEIDPAPDP EAEDTEGKAV ILETELRTED
KVVAEMEEHQ HQVHNVEIVV LED
//
