ID A0A6J5XZ18_PRUAR Unreviewed; 184 AA.
AC A0A6J5XZ18;
DT 07-OCT-2020, integrated into UniProtKB/TrEMBL.
DT 07-OCT-2020, sequence version 1.
DT 02-APR-2025, entry version 16.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=CURHAP_LOCUS46161 {ECO:0000313|EMBL:CAB4288072.1},
GN ORAREDHAP_LOCUS45503 {ECO:0000313|EMBL:CAB4318441.1};
OS Prunus armeniaca (Apricot) (Armeniaca vulgaris).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=36596 {ECO:0000313|EMBL:CAB4318441.1, ECO:0000313|Proteomes:UP000507245};
RN [1] {ECO:0000313|Proteomes:UP000507245}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Rojo Pasion {ECO:0000313|Proteomes:UP000507245};
RX PubMed=33372615; DOI=10.1186/s13059-020-02235-5;
RA Campoy J.A., Sun H., Goel M., Jiao W.-B., Folz-Donahue K., Wang N.,
RA Rubio M., Liu C., Kukat C., Ruiz D., Huettel B., Schneeberger K.;
RT "Gamete binning: chromosome-level and haplotype-resolved genome assembly
RT enabled by high-throughput single-cell sequencing of gamete genomes.";
RL Genome Biol. 21:306-306(2020).
RN [2] {ECO:0000313|EMBL:CAB4318441.1, ECO:0000313|Proteomes:UP000507222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PruArmRojPasFocal {ECO:0000313|EMBL:CAB4318441.1};
RA Campoy J., Schneeberger K., Spophaly S.;
RL Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; CAEKDK010000007; CAB4288072.1; -; Genomic_DNA.
DR EMBL; CAEKKB010000007; CAB4318441.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6J5XZ18; -.
DR OrthoDB; 10009520at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000507222; Unassembled WGS sequence.
DR Proteomes; UP000507245; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.20.120.1750; -; 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 1.
DR SMART; SM00647; IBR; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS51873; TRIAD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000507245};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1..184
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
SQ SEQUENCE 184 AA; 21074 MW; 58DA190B04902CC2 CRC64;
MEGKKIRYQR KVVGLAILLI NDQHDDINPS TFTCDFCVES KHLQDSFKVK GCKGMLDPEH
CRPILPNQIF DRWGSALCEA VVMGSKTDKY LYCPFKDCSA LLVYENGTKR ALCAAVCPHC
KRELCPSCKV PWHTEFDCAQ FQKLSDGDMV KELARKLKWP RCPSCKYYIQ KSSGCNRMKC
RSVM
//
