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Database: UniProt
Entry: A0A6M4PJ82_9ACTN
LinkDB: A0A6M4PJ82_9ACTN
Original site: A0A6M4PJ82_9ACTN 
ID   A0A6M4PJ82_9ACTN        Unreviewed;       313 AA.
AC   A0A6M4PJ82;
DT   07-OCT-2020, integrated into UniProtKB/TrEMBL.
DT   07-OCT-2020, sequence version 1.
DT   18-JUN-2025, entry version 17.
DE   SubName: Full=RNA polymerase sigma factor SigF {ECO:0000313|EMBL:QJS11151.1};
GN   ORFNames=HKX69_17975 {ECO:0000313|EMBL:QJS11151.1};
OS   Streptomyces argyrophylli.
OC   Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2726118 {ECO:0000313|EMBL:QJS11151.1, ECO:0000313|Proteomes:UP000502641};
RN   [1] {ECO:0000313|EMBL:QJS11151.1, ECO:0000313|Proteomes:UP000502641}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=jing01 {ECO:0000313|Proteomes:UP000502641};
RA   Li K.;
RL   Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP053189; QJS11151.1; -; Genomic_DNA.
DR   RefSeq; WP_171154855.1; NZ_CP053189.1.
DR   AlphaFoldDB; A0A6M4PJ82; -.
DR   KEGG; sarg:HKX69_17975; -.
DR   Proteomes; UP000502641; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   CDD; cd06171; Sigma70_r4; 1.
DR   Gene3D; 1.20.120.1810; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR014322; RNA_pol_sigma-B/F/G.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02980; SigBFG; 1.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   PANTHER; PTHR30385:SF4; RNA POLYMERASE SIGMA-E FACTOR; 1.
DR   PANTHER; PTHR30385; SIGMA FACTOR F FLAGELLAR; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
DR   PROSITE; PS00715; SIGMA70_1; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000502641};
KW   Sigma factor {ECO:0000256|ARBA:ARBA00023082};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          116..129
FT                   /note="RNA polymerase sigma-70"
FT                   /evidence="ECO:0000259|PROSITE:PS00715"
FT   REGION          219..238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   313 AA;  34149 MW;  6DD28DE87FDC733E CRC64;
     MSADQGSSKV LTPTLSEAAP KELYALDVLD GFEGVTALEA VPSPAAEPAA EAVPAAQVTG
     AIDTRTLSRS LFLRLATLGE DSPERAYVRD TLIELNLPLV RYAAARFRSR NEPMEDIVQV
     GTIGLIKAID RFDCERGVEF PTFAMPTVVG EIKRFFRDTS WSVRVPRRLQ ELRLALTKAS
     DELSQKLDRS PTVTELAAVL GVSEEDVVDG LAVGNAYTAS SLDSPAPEDD GGEGSLADRL
     GYEDTALEGV EYRESLKPLL AKLPPRERRI IMLRFFANMT QSQIGEEVGI SQMHVSRLLT
     RTLAQLREGL ISD
//
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