ID A0A6P3VUH5_CLUHA Unreviewed; 415 AA.
AC A0A6P3VUH5;
DT 02-DEC-2020, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 1.
DT 28-JAN-2026, entry version 23.
DE SubName: Full=Proteasomal ubiquitin receptor ADRM1 isoform X2 {ECO:0000313|RefSeq:XP_012681599.1};
GN Name=adrm1 {ECO:0000313|RefSeq:XP_012681599.1};
OS Clupea harengus (Atlantic herring).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Clupei; Clupeiformes; Clupeoidei;
OC Clupeidae; Clupea.
OX NCBI_TaxID=7950 {ECO:0000313|Proteomes:UP000515152, ECO:0000313|RefSeq:XP_012681599.1};
RN [1] {ECO:0000313|RefSeq:XP_012681599.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
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DR RefSeq; XP_012681599.1; XM_012826145.2.
DR AlphaFoldDB; A0A6P3VUH5; -.
DR GeneID; 105899024; -.
DR CTD; 11047; -.
DR OrthoDB; 340431at2759; -.
DR Proteomes; UP000515152; Chromosome 4.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 1.10.2020.20:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Receptor {ECO:0000313|RefSeq:XP_012681599.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000515152}.
FT DOMAIN 17..130
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 288..402
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 194..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..264
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..406
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 415 AA; 42544 MW; 395F90642369E136 CRC64;
MSSGALFPSL SSGSRSSSSK YLVEFRAGKM SLKASTVTPD KRKGMVYVQQ TDDSLIHFCW
KDRTSGNVED DLIIFPDDCE FKRVSQCTTG RVFVLKFKAG SKRLFFWMQE PKTDKDEEHC
RKVNEFLNNP PMPGALGSGG SGSHELSALG EGGLQSLLGN MSHNQLMQLI GPTGLGGLGG
LGALAGPGLA SLLGSGGTGS SSTSSSRSQS AAATPSSGSA GARTSSAQAA TTPVTPAASA
PAAAAASPTV TPTTPAAQTP ATPAGVASPT QPIQLSDLQS ILATMNVPNS AASGQGVDLA
TVLTPEIMAP ILSNSEVQER LLPYLPSGES LPQSASEIQN TLTSPQFQQA MSMFSSALAS
GQLGPLMNQF GLPSGAVDAA NKGDVEAFAK AMEGADSKTE GSGDKKEDDE DMSLD
//
