ID A0A6P6DMG2_OCTDE Unreviewed; 287 AA.
AC A0A6P6DMG2;
DT 02-DEC-2020, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 1.
DT 08-OCT-2025, entry version 21.
DE SubName: Full=Sialic acid synthase {ECO:0000313|RefSeq:XP_023561232.1};
GN Name=Nans {ECO:0000313|RefSeq:XP_023561232.1};
OS Octodon degus (Degu) (Sciurus degus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Octodontidae;
OC Octodon.
OX NCBI_TaxID=10160 {ECO:0000313|Proteomes:UP000515203, ECO:0000313|RefSeq:XP_023561232.1};
RN [1] {ECO:0000313|RefSeq:XP_023561232.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (APR-2025) to UniProtKB.
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DR RefSeq; XP_023561232.1; XM_023705464.1.
DR AlphaFoldDB; A0A6P6DMG2; -.
DR FunCoup; A0A6P6DMG2; 1547.
DR GeneID; 101582828; -.
DR CTD; 54187; -.
DR InParanoid; A0A6P6DMG2; -.
DR OrthoDB; 9928645at2759; -.
DR Proteomes; UP000515203; Unplaced.
DR GO; GO:0047444; F:N-acylneuraminate-9-phosphate synthase activity; IEA:TreeGrafter.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR GO; GO:0070085; P:glycosylation; IEA:TreeGrafter.
DR CDD; cd11615; SAF_NeuB_like; 1.
DR FunFam; 3.90.1210.10:FF:000002; Sialic acid synthase; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 2.
DR Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR InterPro; IPR006190; AFP_Neu5c_C.
DR InterPro; IPR036732; AFP_Neu5c_C_sf.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006013; Antifreeze_III.
DR InterPro; IPR013132; Neu5Ac_N.
DR InterPro; IPR051690; Nonulosonic_Acid_Synth.
DR InterPro; IPR013974; SAF.
DR PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR Pfam; PF03102; NeuB; 1.
DR Pfam; PF08666; SAF; 1.
DR PRINTS; PR00357; ANTIFREEZIII.
DR SMART; SM00858; SAF; 1.
DR SUPFAM; SSF51269; AFP III-like domain; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50844; AFP_LIKE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000515203}.
FT DOMAIN 222..281
FT /note="AFP-like"
FT /evidence="ECO:0000259|PROSITE:PS50844"
SQ SEQUENCE 287 AA; 31609 MW; F8B00C673C586875 CRC64;
MPLELELCPG RWVGGQHPCF IIAEIGQNHQ GDLEVAKRLI RTAKMAVEFL HELNVPFFKV
GSGDTNNFPY LEKTAKKGRP MVISSGMQSM ATMKQVYQIV KPLNPNFCFL QCTSAYPLQA
EDVNLRVISE YQKLFPDIPI GYSGHETGIA ISVAAVALGA KVLERHITLD KTWKGSDHSA
SLEPGELAEL VRSVRLVERA LGSPTKQMLP CEMACNEKLG KSVVAKVRIP EGTVLTLDML
TVKVSEPKGC PPEDIFNLVG KKILVTVEED DTIIEESVEN HGKKIKS
//
