ID A0A6P6PAV4_CARAU Unreviewed; 406 AA.
AC A0A6P6PAV4;
DT 02-DEC-2020, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 1.
DT 28-JAN-2026, entry version 25.
DE SubName: Full=Paired box protein Pax-2a-like isoform X25 {ECO:0000313|RefSeq:XP_026117715.1};
GN Name=LOC113096507 {ECO:0000313|RefSeq:XP_026117715.1};
OS Carassius auratus (Goldfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Cyprininae; Carassius.
OX NCBI_TaxID=7957 {ECO:0000313|Proteomes:UP000515129, ECO:0000313|RefSeq:XP_026117715.1};
RN [1] {ECO:0000313|RefSeq:XP_026117715.1}
RP IDENTIFICATION.
RC STRAIN=Wakin {ECO:0000313|RefSeq:XP_026117715.1};
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_026117715.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_026117715.1; XM_026261930.1.
DR AlphaFoldDB; A0A6P6PAV4; -.
DR GeneID; 113096507; -.
DR Proteomes; UP000515129; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0009952; P:anterior/posterior pattern specification; IEA:UniProtKB-ARBA.
DR GO; GO:0048593; P:camera-type eye morphogenesis; IEA:UniProtKB-ARBA.
DR GO; GO:0030902; P:hindbrain development; IEA:UniProtKB-ARBA.
DR CDD; cd00131; PAX; 1.
DR FunFam; 1.10.10.10:FF:000013; Paired box 8 isoform 1; 1.
DR FunFam; 1.10.10.10:FF:000003; Paired box protein Pax-6; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR009057; Homeodomain-like_sf.
DR InterPro; IPR043182; PAIRED_DNA-bd_dom.
DR InterPro; IPR001523; Paired_dom.
DR InterPro; IPR022130; Pax2_C.
DR InterPro; IPR043565; PAX_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR45636:SF19; PAIRED BOX PROTEIN PAX-2; 1.
DR PANTHER; PTHR45636; PAIRED BOX PROTEIN PAX-6-RELATED-RELATED; 1.
DR Pfam; PF00292; PAX; 1.
DR Pfam; PF12403; Pax2_C; 1.
DR PRINTS; PR00027; PAIREDBOX.
DR SMART; SM00351; PAX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00034; PAIRED_1; 1.
DR PROSITE; PS51057; PAIRED_2; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Paired box {ECO:0000256|ARBA:ARBA00022724};
KW Reference proteome {ECO:0000313|Proteomes:UP000515129};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 15..141
FT /note="Paired"
FT /evidence="ECO:0000259|PROSITE:PS51057"
FT REGION 142..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..177
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..219
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 406 AA; 43683 MW; 4302EA9D6F7C9FAC CRC64;
MDIHCKADPF SAMHRHGGVN QLGGVFVNGR PLPDVVRQRI VELAHQGVRP CDISRQLRVS
HGCVSKILGR YYETGSIKPG VIGGSKPKVA TPKVVDKIAD YKRQNPTMFA WEIRDRLLAE
GVCDNDTVPS VSSINRIIRT KVQQPFHPSS DGTGTPLTTA GHTIVPSTAS PPVSSASNDP
VGSYSINGIL GIPRSNGEKR KRDDDGSDGS GPNSDSQGSV ESLRKHLRAD AFTQQQLEAL
DRVFERPSYP DVFPTSEHIK PEQANEYTLP ALNPGLDEVK PSLSTSVSSD LGSSVSQSYP
VVTGRDMAST TLPGYPPHVP PTGQGSYPTS TLAGMVPGSD FSGNPYSHPQ YTTYNEAWRF
SNPALLMPHH GAPPLPLLPL PMTATSYHGN PIKLQDHGRG LQIVPV
//
