ID A0A6P6UYU3_COFAR Unreviewed; 443 AA.
AC A0A6P6UYU3;
DT 02-DEC-2020, integrated into UniProtKB/TrEMBL.
DT 08-OCT-2025, sequence version 2.
DT 28-JAN-2026, entry version 24.
DE SubName: Full=Transcription factor bHLH110 isoform X1 {ECO:0000313|RefSeq:XP_027094752.2};
GN Name=LOC113714842 {ECO:0000313|RefSeq:XP_027094752.2};
OS Coffea arabica (Arabian coffee).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Gardenieae complex;
OC Bertiereae - Coffeeae clade; Coffeeae; Coffea.
OX NCBI_TaxID=13443 {ECO:0000313|Proteomes:UP001652660, ECO:0000313|RefSeq:XP_027094752.2};
RN [1] {ECO:0000313|Proteomes:UP001652660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=40002058; DOI=10.3390/foods14040614;
RG RefSeq;
RA Tenea G.N., Cifuentes V., Reyes P., Cevallos-Vallejos M.;
RT "Unveiling the Microbial Signatures of Arabica Coffee Cherries: Insights
RT into Ripeness Specific Diversity, Functional Traits, and Implications for
RT Quality and Safety.";
RL Foods 14:614-614(2025).
RN [2] {ECO:0000313|RefSeq:XP_027094752.2}
RP IDENTIFICATION.
RC TISSUE=Leaves {ECO:0000313|RefSeq:XP_027094752.2};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_027094752.2; XM_027238951.2.
DR AlphaFoldDB; A0A6P6UYU3; -.
DR GeneID; 113714842; -.
DR OrthoDB; 760019at2759; -.
DR Proteomes; UP001652660; Chromosome 10e.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR CDD; cd11393; bHLH_AtbHLH_like; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR045239; bHLH95_bHLH.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR045843; IND-like.
DR PANTHER; PTHR16223:SF56; TRANSCRIPTION FACTOR BHLH110; 1.
DR PANTHER; PTHR16223; TRANSCRIPTION FACTOR BHLH83-RELATED; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP001652660};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 322..371
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 387..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..34
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 443 AA; 48018 MW; CD81E7A6C2690D02 CRC64;
MESTSKIPHH HRHLQQQHPL QGHQLVGSSS TSTSTTTLGA SGFGAALSSH AWTPNTNLNS
AGFGSAANTA ILNSRNPRLE NDILVSSLNG SMTQDFSFSW ANGSRGNNFT NQSSHDLQLE
MIKREFSESY SNFSEMISSP SSSVEDVQLP IQATDYRRSE YREINDPNVK LLLRSLSSGD
RNNDFHRSCP GELYCSTSSS SSLGATPKRG TFSQIYPTIN VSEINQTSLA NSSSFHMNSQ
ALDLVNSARF SGIFCLPMVD QLGLSKNGSL SYGYDYLSQS IPMPISEPSN ITPLSNGVTE
TKWSDISLEP KVPQAAPKRS RSESRASCPP FKVRKEKLGD RIAALQQLVA PFGKTDTASV
LMEAIGYIKF LQNQVETLSV PYLKSSRNKS SRTVHGGAVE NGGEERKRDL RSRGLCLVPM
SCLSYVADGG GGVWPPPSFG GGT
//
