ID   A0A6P7YFU1_9AMPH        Unreviewed;       728 AA.
AC   A0A6P7YFU1;
DT   02-DEC-2020, integrated into UniProtKB/TrEMBL.
DT   02-DEC-2020, sequence version 1.
DT   28-JAN-2026, entry version 22.
DE   RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN   Name=ZNF750 {ECO:0000313|RefSeq:XP_030063903.1};
OS   Microcaecilia unicolor.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Gymnophiona; Siphonopidae; Microcaecilia.
OX   NCBI_TaxID=1415580 {ECO:0000313|Proteomes:UP000515156, ECO:0000313|RefSeq:XP_030063903.1};
RN   [1] {ECO:0000313|RefSeq:XP_030063903.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (AUG-2025) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_030063903.1; XM_030208043.1.
DR   AlphaFoldDB; A0A6P7YFU1; -.
DR   FunCoup; A0A6P7YFU1; 589.
DR   GeneID; 115473250; -.
DR   KEGG; muo:115473250; -.
DR   CTD; 79755; -.
DR   InParanoid; A0A6P7YFU1; -.
DR   OrthoDB; 8933073at2759; -.
DR   Proteomes; UP000515156; Chromosome 6.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR   GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR   InterPro; IPR039363; ZNF750.
DR   InterPro; IPR039064; ZNF750_Znf.
DR   PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR   PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR   Pfam; PF15269; zf-C2H2_7; 1.
PE   4: Predicted;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000515156};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          6..57
FT                   /note="Zinc finger protein 750-like zinc finger"
FT                   /evidence="ECO:0000259|Pfam:PF15269"
FT   REGION          64..105
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          390..494
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          654..728
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..79
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        425..436
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        482..492
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        666..678
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   728 AA;  80987 MW;  CAD67C70C79A9D9C CRC64;
     MSLLKERKPK KPHYIPRPPG KPFKYKCFQC PFTCNEKSHL FNHMKYGLCK NSITLVTEQD
     RVIKSPKSNS LEPKQTNQLE PLVKSSPSSS TTSRPLILDS KPQHAATKDE VKENLNLQNH
     GTSKPAPQPE RLAMQKEIAL STTTEDVMNK LPVLESVVRP SAFVPIGEHR QIKGTENKEV
     PELLSTSHLN SKNVPYYTKS AFHSPVHSWK TGPSFASPDF PKISSAKGFG SIPCCMPPMI
     PEYPPHFYTE QGLTSICSTY QFPGSPHECE NTLLPVYATP DQRHFLTHPA QTSGTLLSKP
     MSSLPMDRYR LMQQLHPNPP LPYALYRAPE HLYPAYNLKP PYITAGVNKD QNSHLIEDTT
     LLYPCSSSPS RIYPLALHKK HNECGREVSL LQTKNNMKDS QNETENAKMS PRAGTAATGS
     PGRPSPTNFT QTSQGSDALF GLNKCSPSND QSEETLTAFR PVKKSTDTND SYNLQAQREG
     ESSSSTDVTS KSMYHQHPNH PIISQGALFN AMDDNGLAPL NLSKKSDSIT HEFIAKRCKN
     AFLSKGQSFM DIQDMPLNLS VRDSCNTIGL KTSVHSPTHD SVTSTSEKLE PENLSTQVYD
     IDRHKNSEED KNVCATQSAE MQDLQDLRIM DHCDEQKQTA AVALCQLAEY SPGKIRMGNE
     DDDSQDNGSN QAEATHSSSK NEENLCNHKA HGQKRTQKES AKSQPASKKT KVVNSGRVFT
     LRKRARVS
//