ID A0A6P8AU65_PYRGI Unreviewed; 668 AA.
AC A0A6P8AU65;
DT 02-DEC-2020, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 1.
DT 28-JAN-2026, entry version 23.
DE RecName: Full=DBF4-type domain-containing protein {ECO:0000259|PROSITE:PS51265};
GN ORFNames=PgNI_08740 {ECO:0000313|RefSeq:XP_030978447.1};
OS Pyricularia grisea (Crabgrass-specific blast fungus) (Magnaporthe grisea).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX NCBI_TaxID=148305 {ECO:0000313|Proteomes:UP000515153, ECO:0000313|RefSeq:XP_030978447.1};
RN [1] {ECO:0000313|Proteomes:UP000515153, ECO:0000313|RefSeq:XP_030978447.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NI907 {ECO:0000313|Proteomes:UP000515153,
RC ECO:0000313|RefSeq:XP_030978447.1};
RX PubMed=30835262;
RA Gomez Luciano L.B., Jason Tsai I., Chuma I., Tosa Y., Chen Y.H., Li J.Y.,
RA Li M.Y., Jade Lu M.Y., Nakayashiki H., Li W.H.;
RT "Blast fungal genomes show frequent chromosomal changes, gene gains and
RT losses, and effector gene turnover.";
RL Mol. Biol. Evol. 36:1148-1161(2019).
RN [2] {ECO:0000313|RefSeq:XP_030978447.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NI907 {ECO:0000313|RefSeq:XP_030978447.1};
RG NCBI Genome Project;
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_030978447.1}
RP IDENTIFICATION.
RC STRAIN=NI907 {ECO:0000313|RefSeq:XP_030978447.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
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DR RefSeq; XP_030978447.1; XM_031128732.1.
DR AlphaFoldDB; A0A6P8AU65; -.
DR GeneID; 41963640; -.
DR KEGG; pgri:PgNI_08740; -.
DR OrthoDB; 21380at2759; -.
DR Proteomes; UP000515153; Chromosome V.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000515153};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 599..648
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 371..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 539..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..203
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..223
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..400
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 668 AA; 74784 MW; 8B2CC9A44F541032 CRC64;
MATVSLIPSP VSFHQTAMSS RSRVPLSSNP NAANSPMRPM AVAHPKPVKR SHASNQREEL
YGQPPPAKKQ MISNPSTYRV TARSPVKART TTHTITQSRA VGGHRDRDAA SQQHVKAQLA
DEDVNDFKKW AAAQKQQFVK HVFYFDNLPQ EVLPKIERQI AALGAREDKF FSISISHVVT
TRPIPQPQTS QKPKLDVSTK TDRDEQEPQT INPSLLSRNL DSTCTKRKLF DTHPAGRRPP
IQLGEDVVRR PKAPRQQNDI LGRALTMGKK IWSLEKMQRI LDMLTESDPY RAATLGQGGR
TIKTVEQSNP LQMLNKERVS GPSDRDPTAS TKEMHIFKGP FIYIYDIEQK QRPIMAREYA
KVADKMKGDW PQFRASGSGR CPFVEDHDQE KHPKKEREVT RQAAVNAAVG SAPKLQPPTQ
ISRPKPITGK RPLAEMSEVS TNRILFPSKT TTGGNALMDS AQGSKLSKED ALSNAFISTN
RSRPARIFAG EPVASGLQAS NITSAIRSQM ISSTTGTIAS NKSGVSKEVL GLQRKVLAKS
GSISQDPSSR RHAEMSVDSG PLSRSTSLGN PRLIFEGEET QHRRTHSVPS KLQPKPKKRD
PKPGYCENCQ DKFADFEEHI QSRTHRKFAE NDENWEDLDR LLQQLERQPL PHHHLYSDET
VEQNYDQY
//
