ID A0A6P8HBI8_ACTTE Unreviewed; 429 AA.
AC A0A6P8HBI8;
DT 02-DEC-2020, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 1.
DT 28-JAN-2026, entry version 24.
DE SubName: Full=TNF receptor-associated factor 4-like {ECO:0000313|RefSeq:XP_031553804.1};
GN Name=LOC116290835 {ECO:0000313|RefSeq:XP_031553804.1};
OS Actinia tenebrosa (Australian red waratah sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Actiniidae; Actinia.
OX NCBI_TaxID=6105 {ECO:0000313|Proteomes:UP000515163, ECO:0000313|RefSeq:XP_031553804.1};
RN [1] {ECO:0000313|RefSeq:XP_031553804.1}
RP IDENTIFICATION.
RC TISSUE=Tentacle {ECO:0000313|RefSeq:XP_031553804.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_031553804.1; XM_031697944.1.
DR AlphaFoldDB; A0A6P8HBI8; -.
DR GeneID; 116290835; -.
DR KEGG; aten:116290835; -.
DR InParanoid; A0A6P8HBI8; -.
DR OrthoDB; 5973446at2759; -.
DR Proteomes; UP000515163; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005164; F:tumor necrosis factor receptor binding; IEA:TreeGrafter.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR GO; GO:0043122; P:regulation of canonical NF-kappaB signal transduction; IEA:TreeGrafter.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.210.10; Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR002083; MATH/TRAF_dom.
DR InterPro; IPR012227; TNF_rcpt-assoc_TRAF_met.
DR InterPro; IPR008974; TRAF-like.
DR InterPro; IPR049342; TRAF1-6_MATH_dom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR10131; TNF RECEPTOR ASSOCIATED FACTOR; 1.
DR PANTHER; PTHR10131:SF94; TNF RECEPTOR-ASSOCIATED FACTOR 4; 1.
DR Pfam; PF21355; TRAF-mep_MATH; 1.
DR Pfam; PF02176; zf-TRAF; 1.
DR PIRSF; PIRSF015614; TRAF; 1.
DR SMART; SM00061; MATH; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 3.
DR PROSITE; PS50144; MATH; 1.
DR PROSITE; PS50145; ZF_TRAF; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207}; Reference proteome {ECO:0000313|Proteomes:UP000515163};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 36..80
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 92..138
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 271..424
FT /note="MATH"
FT /evidence="ECO:0000259|PROSITE:PS50144"
FT ZN_FING 36..80
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT ZN_FING 92..138
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT REGION 243..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 429 AA; 49610 MW; C3B93FB073A6A222 CRC64;
MMPREDMAKH LLQECEWREI PCPHCDQMTG FCQLKAHEKI CEQVTVECTN AECDVMKPRM
EMTKHLEQEC EWRQVSCPHC NDDHHAFKLQ DHIKVCPKTP VRCPNECGVE TINEEIADHV
TNECPLTEVP CIYQQFGCQF LMQRKENRME EHMEKATKDH LALACEELKL LQENNGVLSN
RVSSLQDENE SMFHRLFLLQ EESMSKFDRL FSRLSSVEDR NAFLSGRLSD VQNENAAMSH
RLLHQDEIKK PNKKTVKKEE KKKEEPSIPY TGTFVWKIGN VKKLLSEAKQ GRSTVLFSEP
FYTANHGYKL RAMLYPNGAK NENAGHMSIY AQIKRGEYDD TLPWPFGKDI TFTLVDQKIN
IKNRKNIKDT IHSKNLLDSF LQCFQRPTSD TNKSIPGLST FVKHDKLMSK SYAKGDSMVI
IVDVSEATT
//
