ID A0A6P8XRC9_DROAB Unreviewed; 174 AA.
AC A0A6P8XRC9;
DT 02-DEC-2020, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 1.
DT 28-JAN-2026, entry version 23.
DE RecName: Full=Proteasomal ubiquitin receptor ADRM1 homolog {ECO:0000256|ARBA:ARBA00070663};
GN Name=LOC117578127 {ECO:0000313|RefSeq:XP_034119216.1};
OS Drosophila albomicans (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7291 {ECO:0000313|Proteomes:UP000515160, ECO:0000313|RefSeq:XP_034119216.1};
RN [1] {ECO:0000313|RefSeq:XP_034119216.1}
RP IDENTIFICATION.
RC STRAIN=15112-1751.03 {ECO:0000313|RefSeq:XP_034119216.1};
RC TISSUE=Whole Adult {ECO:0000313|RefSeq:XP_034119216.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- FUNCTION: May function as a proteasomal ubiquitin receptor. May promote
CC the deubiquitinating activity associated with the 26S proteasome.
CC {ECO:0000256|ARBA:ARBA00054744}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
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DR RefSeq; XP_034119216.1; XM_034263325.2.
DR AlphaFoldDB; A0A6P8XRC9; -.
DR GeneID; 117578127; -.
DR CTD; 31433; -.
DR OrthoDB; 340431at2759; -.
DR Proteomes; UP000515160; Chromosome X.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Receptor {ECO:0000313|RefSeq:XP_034119216.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000515160}.
FT DOMAIN 39..152
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
SQ SEQUENCE 174 AA; 20288 MW; 150F95F0A0CA9374 CRC64;
MKSFNKIQIS SSISISIVFL LSHTHISFDL FKLDSDSADA DRHLVEFKAG RMIQGAQMVE
PDNRKGLIYL YRDEAYDLHF CWMDRRRMAV EIDIIVSPGT LEFHRVESCK TGRIYVLKFR
RSPNRLFFWM QDPRFEHDAE ICAQVNELLR SNTNSDDDYS LKSVKGANLK QSES
//
