ID A0A6P8XXZ3_DROAB Unreviewed; 501 AA.
AC A0A6P8XXZ3;
DT 02-DEC-2020, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 1.
DT 28-JAN-2026, entry version 22.
DE SubName: Full=Choline/ethanolamine kinase isoform X3 {ECO:0000313|RefSeq:XP_034118209.1};
GN Name=LOC117577404 {ECO:0000313|RefSeq:XP_034118209.1};
OS Drosophila albomicans (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7291 {ECO:0000313|Proteomes:UP000515160, ECO:0000313|RefSeq:XP_034118209.1};
RN [1] {ECO:0000313|RefSeq:XP_034118209.1}
RP IDENTIFICATION.
RC STRAIN=15112-1751.03 {ECO:0000313|RefSeq:XP_034118209.1};
RC TISSUE=Whole Adult {ECO:0000313|RefSeq:XP_034118209.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
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DR RefSeq; XP_034118209.1; XM_034262318.2.
DR AlphaFoldDB; A0A6P8XXZ3; -.
DR GeneID; 117577404; -.
DR OrthoDB; 3649325at2759; -.
DR Proteomes; UP000515160; Chromosome 2L.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0004103; F:choline kinase activity; IEA:TreeGrafter.
DR GO; GO:0004305; F:ethanolamine kinase activity; IEA:TreeGrafter.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:TreeGrafter.
DR CDD; cd05156; ChoK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR Gene3D; 3.30.200.20; Phosphorylase Kinase, domain 1; 2.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR PANTHER; PTHR22603:SF93; RE24176P; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|RefSeq:XP_034118209.1};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000515160};
KW Transferase {ECO:0000313|RefSeq:XP_034118209.1}.
FT REGION 101..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..352
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 501 AA; 58078 MW; 029CEA2B472E23C8 CRC64;
MQNMFYDLQS ATLEEIRQAF SRICRDYLTG RWKVATPEQL VVKRISGGLS NFLYYVSLPD
LDDLDQQEVL KIEQEQKNKQ EVAVESPESL ILDIVSGGDG DINADDDDDT AQRANPANKR
RRFDSDCGDS TFLKRLHTAK QEPREVLLRI YGQTHGDHAL ESMITESVVF TLLSERNFGP
KLYGIFPGGR IEQYIPARSL TTMEMSNAEI SMKIAEKMGE IHSLNIPMSK EPDWIWNCMN
RWLTSVDSII KGKIESKPNS TVLQKQRELM GTIDYVKEMA WLRSVIDAGA YPVVFCHNDL
QEGNILLRET NRTRDTRTPL ESISILRSNF NETLGYSSDG NNHLESMQNP SSCDELDTTD
DSASIKSEHE PDLIIIDFEY CAYNYRGFDL ANHFIEWTFD YTNPQFPYFY HIQQQYSTAA
QRRDFIYTYL RKFHEDELYE PTTSDLNMIE TEIQLFTMLS HLFWSLWSVV NVTSAIQFGY
WEYGIARILE YQQLKTNFLA K
//
