ID A0A7E6DK64_9CHIR Unreviewed; 508 AA.
AC A0A7E6DK64;
DT 10-FEB-2021, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2021, sequence version 1.
DT 28-JAN-2026, entry version 22.
DE RecName: Full=WD repeat, SAM and U-box domain-containing protein 1 {ECO:0000256|ARBA:ARBA00020894};
GN Name=WDSUB1 {ECO:0000313|RefSeq:XP_035879320.1};
OS Phyllostomus discolor (pale spear-nosed bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae;
OC Phyllostominae; Phyllostomus.
OX NCBI_TaxID=89673 {ECO:0000313|Proteomes:UP000504628, ECO:0000313|RefSeq:XP_035879320.1};
RN [1] {ECO:0000313|RefSeq:XP_035879320.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_035879320.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
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DR RefSeq; XP_035879320.1; XM_036023427.1.
DR AlphaFoldDB; A0A7E6DK64; -.
DR FunCoup; A0A7E6DK64; 1623.
DR GeneID; 114495596; -.
DR CTD; 151525; -.
DR InParanoid; A0A7E6DK64; -.
DR OrthoDB; 10064100at2759; -.
DR Proteomes; UP000504628; Chromosome 4.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd16655; RING-Ubox_WDSUB1-like; 1.
DR CDD; cd09505; SAM_WDSUB1; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR052085; WD-SAM-U-box.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR020472; WD40_PAC1.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46573; WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR46573:SF1; WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF04564; U-box; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00454; SAM; 1.
DR SMART; SM00504; Ubox; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS51698; U_BOX; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000504628};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 82..123
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 125..160
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 267..308
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 309..343
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 364..428
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 435..508
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
SQ SEQUENCE 508 AA; 56493 MW; 98805F0A80C8EE40 CRC64;
MNTGHQGCPP TWVSQSAEFR LAVRDILLQG KNMVKLIHTL ADHGDDVNYC AFSSSLLATC
SLDKTIRLYS LSDFTELPHS PLKFHTYAVH CCCFSPSGHI LASCSTDGTT VLWNTQNGQT
LAVLEQPRGS PVRVCRFSPD STCLVSGAAD GTVVLWNAQS YKLHRCGSVK DGSLVACAFS
PSRNLFVTGS SCGDLTVWDD KMKCLHSEKA HDLGITCCDF SSQPVSDGEQ SLQFFRLATC
GQDCQIKIWV VPLSHILGFE LKYKSTLSGH CAPILACAFS HNGQLLVSGS VDKSVIVYDI
NTENILHTLT QHTRYVTTCA FAPNILLLAT GSMDKTVNIW QFDLEMLCQA RSTEDQLKPF
TEDWSEDDVS TWLCTQELKD LVGVFKMNNI DGKELLNLTK ESLADDLKIE SLGLRSKVLR
KIEELRTQVK TLSSEIPDEF ICPITRELMQ DPVIASDGYS YEKEAMENWI SKKKRTSPMT
NLVLPSVVLI PNRTLKMAID RWLETHKK
//
