ID A0A7G5BA67_9CAUD Unreviewed; 4219 AA.
AC A0A7G5BA67;
DT 10-FEB-2021, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2021, sequence version 1.
DT 08-OCT-2025, entry version 21.
DE RecName: Full=Helicase C-terminal domain-containing protein {ECO:0000259|PROSITE:PS51194};
GN ORFNames=23F_00028 {ECO:0000313|EMBL:QMV33190.1};
OS Ralstonia phage Gerry.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Cimandefvirus; Cimandefvirus Ggerry.
OX NCBI_TaxID=2759727 {ECO:0000313|EMBL:QMV33190.1, ECO:0000313|Proteomes:UP000515274};
RN [1] {ECO:0000313|EMBL:QMV33190.1, ECO:0000313|Proteomes:UP000515274}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Trotereau A., Boyer C., Torres-Barcelo C.;
RT "Ralstonia phages.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; MT740739; QMV33190.1; -; Genomic_DNA.
DR Proteomes; UP000515274; Segment.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006304; P:DNA modification; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd00254; LT-like; 1.
DR Gene3D; 1.10.530.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR052933; DNA_Protect_Modify.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C-like.
DR InterPro; IPR040561; LPD38.
DR InterPro; IPR023346; Lysozyme-like_dom_sf.
DR InterPro; IPR011639; MethylTrfase_TaqI-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR008258; Transglycosylase_SLT_dom_1.
DR PANTHER; PTHR41313; ADENINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR41313:SF1; DNA METHYLASE ADENINE-SPECIFIC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07669; Eco57I; 1.
DR Pfam; PF18857; LPD38; 1.
DR Pfam; PF01464; SLT; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF53955; Lysozyme-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000515274}.
FT DOMAIN 2623..2807
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 35..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 580..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 688..739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 774..833
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 847..901
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1008..1028
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1093..1141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1322..1443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3289..3314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2976..3010
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 182..199
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 585..605
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 695..717
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 782..793
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..833
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1008..1018
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1097..1113
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1119..1134
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1351..1361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1377..1392
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1432..1443
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4219 AA; 455816 MW; D226F6823FFD3F62 CRC64;
MADNQPFFAP LFDTTEDTNA SIYQLPPLQE ALKSEPDAAP AVKSRGMPTA SDVSRRAEEL
GIDPKFALSI FKQESSGNFN ERDSNKGAIG GMQVMPGTYK AMMGTTEGMR DPWNNLEAGL
RYIAYGQRAL GTKDPALLAA GYHAGYDRKD LKQGIIPDVS DGAKRTRDYA REVAARAGGS
APAGKVASAD SAAPATPSIP SLQSALDAQE PGRYEVLADP GADVLTRLNT GDDKDRYELA
SPDEISRFEA GKKESVGDAA KSFLGKSLKA GMYDLAGAGA KLLDAVNPWT LSESDAATLF
KSDPAKLKDY QDNSVAMILS RFARRMSHNS EDAMKEISPG AELRYGHKEY ATTDLDKAAY
ASPVKVIGDV VRNLPTQVGL AISAYLTRGA AAQAESQALK AGLTAEAAKQ AAIQAGAKTM
ATIGAVSEGA IGYAQQANQA REDAEKVKQA DLEKSPEYQK LLANGYTPET AKQKLAAVTA
EQAGVVAGVV DAAVNKVGGH FLGKIMTEGG KFVPRVMKGF VNEGATEAIQ SPGEQYAQNS
AVKRNINPNQ DLSEGVLENA VQGLVVGGVS GGGFAGAMGR GHSSAAPNNA APAVPAAPAA
PENQAPAAPA APVAAAPAAP VAEPAAPAGP IERAVGKVVP ESKQVVGDDG TVYNVKVGDN
GVEVAPIEPV AEAAPALTER EKALQEIGDN AASEKPPKPE PAAKVEEAAS ARVEEPAAKA
PAGPTDTRAP AGADLSAMDE PALRERMKYL AGQAKRTGGW DKMLVAERKR VEAEISKRKN
GQPAAQVEQA AEPAPEKTAS GAFVKQADAN DAMRTAARET GKPHQVVERE EAGRVVFDVR
PMEEANGANA RRAEPAGAPV TAAEQASAAP AAPAAERPAR AAKTAPTAGE PGAAAGEATA
EPAALTVKAA SGKVYPTKGE RLPKAGVVPA NLGNDGIVYV GRPNSLHFHV ADRHSKAAGG
FSDTGFVTPD GQYLNREEAL AWVNTHEAKV KPSENMGASL DAIDYREQVP ESKRKAPEAA
EDTAAKPAAA PAEAVKWFGT REQAKEANGD RSVIVSNDGH IIDGHHQALA AKEEGKDVKA
IVLDAPVDQA LEAVKNSPSA QPAAEPAPAA PKKPSTKAEP NRVHRVLGDA RKGDTVTPSA
DIGYSKAGQS YEIEAIGRNG ETTVRNTATG GRTTWSRAEL ERAARMGVTI EKQQPAGAEA
KGASAGKASG GVDFSKNRLF TEDAVEKARA RMRRKLKSTA FTGLDPELVT DGMTIAGAYI
EAGVREFGAY AKAMVEDFGA EVKPYLLSFY EAVRHFPGLE TEGMTAPQEA GRLHAELLSQ
NETAQEAQHD TEANPARPGA GDEGQSAAAV RGDEGGRDAV RVSESADGGR AGVAERGAQH
AGERPAVPED QRPANADAGS EQSAEGSRER GATAGSRGDQ QPASAAANHR IRPGDLKREG
SWKDTAERNV EIVELVKQLE KGGRVATPDE RALLARYTGW GASEIANGIF PDRNGRYKDA
SWQALGERLK AALTPAEYAD ARRTMQYAHY TSEGVIRAIY AGLDRLGFKG GAILEPGMGV
GHFNGLMPSQ MAAHSSYTGI EFDPITGAIA RALYPQSNVI VGDYTKTALP KDFFDAAIGN
PPFSSTVVSN DAEYKKHGFM LHDYFFAKTL DRVKPGGVVA FVTSKGTMDK ASSRAREFMA
ERANLIGAVR LPQTAFKENA GTEVVTDVLF LQKRGPGIPD NGVKWLGTKE VDTPQGKAPV
NEYFSDHPEM VLGEHAKTGS MYRADEYTVV PRAGEDIEQA FAKAIQSLPE GDYRPARGSA
AERAFVQDRD FNPKAKKEGG LYVADDGRLM QVEDGAGADL THRLNSEGKR IELKPKERAW
LRGWVSLRDA LKQAQLDQLT DGDWQGSLQA LNGAYDAFVK EHGNILAFST IERENPDGTT
SVTRRLKNAP LMTIDAEGAL AHALERINED GTISKGAVLQ DRVLKRPTEP VINTTQDAMF
VALDRHGAFD VDTVARLAGV SREQAIADLG TAIYEAPGAS WQMADEYLSG NVVRKLKEAQ
AATEIDKRYS RNVEALLAVQ PRPLGPQDIS VKLGANWVKP ADIEAFARDA LGERMDVAYH
EKLNDWTVAS VERAITEWGF EKMSASQILD ATLNNRQIKV TFRDQDGKTH VDIEATTKAN
DISQKMKDAF RRWIWTDAER ADRLTRYYNE NFNNIAPRAF DGSHLTLPGM SSRYALYDHQ
KRAVWRQIQA GDTYLAHAVG AGKTMEMIAG GMEQKRLGLI DKPVYAVPNH MLAQFAREFM
ELYPAANIMV ADETNFHTHN RRRFIAQAAL NNPDAIVMTH SSFGRVGMSE EFTKSYIEKQ
IGEWKEILAE TDKGDRLTRK QVERRIEQLE RRIEAKQATE KKDRVLTFEE LGADMLFVDE
LHEFRKLDFA TNQGNVKGID PSGSQRAFDL MMKVEYLRGK KPGRSLVGAS GTPVTNTMGE
LYTAQRLFQP KQLEEDGLTS FDAWANQYGD IVAGFEQNAA GGYEVVARFA KFQNVPELMR
RVRSFMDILT SSNLGELVKR PTVEGGQREV RITPAPDGYK EYQQELQQRI TAIRQRKGPP
KKGEDIILRV IGDGRFSAID MRFVDPSRAN DPDSKLNQML DALIDDYHAM ADNEYSDTAT
SKPDPIKGAS HIIFTDIGLG EQSAASRGFD MRRWIEKRLT DGGVPADHIA FMRDYKLHAK
KERLFADMRE GKKRILIGGK DMETGVNVQK RLATLDHLDA PWFPASVEQR EGRPVRQGNQ
NKQVRLRAWA TKGSYDSTMW GMNARKARFI EQAMNGDDTV RSLEDVSEAS AFEMAAALAS
GDERYMKLAG LKQDVDRLER LRHAHFDEQR RLSVEKQYAV DAVDRNERRV ADLTEAIKQR
TPIRAGEFLA QAGKAEFDAR EQFSAALFDE FKALTGKEFN GEQVIGRIGG FPITFYGLKG
QGSDAYVAGV HVGIPGDPDP IITYPIRGEF AINGIAARAA NQVNSLDRMV VEAKDRIEQS
QRKIEQIESR LGTPFPEEGE LLEKVVALNQ LENELTAEKA AEGGEQVSAD AAAATVETEG
GEDGPRYSVA PGVDREQSVP VTRIQTFRNV RGTTVELSMT LRDGNVGDLI GRLLDRGRVV
LHDDAGSLPG KNAPRGVQAS TMPDGTIHMV GANLNAQSAV PVLLHEMFHS GVKPLVGEAA
WGKLMTRLDG LLRQSERSTG RAREFYDAAF RRMRAAAHAG DARVMNAEEF GAYAIEEYSS
APAAVRAWVD DVVGAIKAWL LRRFGTQLGA VTPAQLRALA VAALRSEPRA GGDAPRNSVK
APLNPVEAGL TPPAPTRFDR FQAAVQDNMN RVKQVQERIK KLTGLKELGF ADYYRAEANR
PGRVAARLED AQKHLTGPLM ERLAKSGHTQ AQLEELLHAQ HAEERNEKIA EINKDMPDGG
SGMMTAEANA ILEKYKGATE LKAIAQQARD IARATLDLKL AYGLIDQTTH DTLSTGYENY
VPLKGDGEYG PKIKRAMGHE ERAEHILENI ARDYDQAVAA GEKNIARQSL LALVAEHEDP
SLWTIGIPPR GRRIAGQVFN VVDPSLPKGQ QTIGSFSARS QVDAFLEGAG PKAASYLVLD
SGGERVQQFV RPLQDNEVMV YVKGEPVRIQ IYDEALARQL RPLDPPKMNW ALEKMRSLNR
YLSKIYTGYN PSFILRNAAR DALTGTINMV GHEGAGVAAK AWAKYPGAVK ALGQWAATGN
APVGKTGEYL KEYRMHGGKT GASWMSDLEA KGKELSRMYE DAYGASGYLK DGQNLKAAKV
AGRKIVGGMA HVVEIANQAT ENALRLSLYM TLRESGASPG KAAQAAKSVT VDFDRKGTMT
GALGAVYLFL NPAVQGTANA MRTLASGEHR GQAFAALGML ATLGFYAAAS GMDDDKDRWL
GEGWDGRTKN FVMMFGDHTL KVPLSQEFTP AYAFGVALAE AMRGEGAMKS AVRMVSSFLD
AYFPLNGAYN PDSDNHAEDA LLAAMPTIIK PGAESVFNRN HFGSQIVPET TSTKSQPDNL
KMYRGTKGTV YDALAQQIAA AGELAGAGRY QNDITKISPE TLKYVWRTYT GGLGQFVTDS
IGAASLATEP GEMSSSDIPI AKDFWRAQDV KPIRSRYYDL AREAKEAATE FQQAKKAGDG
EAIDSIFARP GQAELIALDK MFKKSSHAAA AIRDEEVTVN ADKSLSTSEK RDRLKELEKQ
EESIYRDALD VFKTSIPSK
//
