ID   A0A7G9R9W9_9ACTN        Unreviewed;       584 AA.
AC   A0A7G9R9W9;
DT   10-FEB-2021, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2021, sequence version 1.
DT   28-JAN-2026, entry version 22.
DE   SubName: Full=Selenocysteine-specific translation elongation factor {ECO:0000313|EMBL:QNN52394.1};
GN   Name=selB {ECO:0000313|EMBL:QNN52394.1};
GN   ORFNames=H9L09_18240 {ECO:0000313|EMBL:QNN52394.1};
OS   Nocardioides mesophilus.
OC   Bacteria; Bacillati; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=433659 {ECO:0000313|EMBL:QNN52394.1, ECO:0000313|Proteomes:UP000515947};
RN   [1] {ECO:0000313|EMBL:QNN52394.1, ECO:0000313|Proteomes:UP000515947}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KACC 16243 {ECO:0000313|EMBL:QNN52394.1,
RC   ECO:0000313|Proteomes:UP000515947};
RA   Hyun D.-W., Bae J.-W.;
RT   "Genome sequence of Nocardioides mesophilus KACC 16243T.";
RL   Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; CP060713; QNN52394.1; -; Genomic_DNA.
DR   RefSeq; WP_187578236.1; NZ_CP060713.1.
DR   AlphaFoldDB; A0A7G9R9W9; -.
DR   KEGG; nmes:H9L09_18240; -.
DR   Proteomes; UP000515947; Chromosome.
DR   GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0035368; F:selenocysteine insertion sequence binding; IEA:TreeGrafter.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0000049; F:tRNA binding; IEA:TreeGrafter.
DR   GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR   GO; GO:0016259; P:selenocysteine metabolic process; IEA:TreeGrafter.
DR   CDD; cd04171; SelB; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR057335; Beta-barrel_SelB.
DR   InterPro; IPR050543; eIF2G.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR015191; SelB_WHD4.
DR   InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR004535; Transl_elong_SelB.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR00475; selB; 1.
DR   PANTHER; PTHR42854; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER; 1.
DR   PANTHER; PTHR42854:SF3; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED; 1.
DR   Pfam; PF25461; Beta-barrel_SelB; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF09107; WHD_3rd_SelB; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50447; Translation proteins; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Elongation factor {ECO:0000313|EMBL:QNN52394.1};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Reference proteome {ECO:0000313|Proteomes:UP000515947}.
FT   DOMAIN          1..169
FT                   /note="Tr-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51722"
SQ   SEQUENCE   584 AA;  61041 MW;  F4702BAC664FEFCB CRC64;
     MYVVATAGHV DHGKSTLVTA LTGSDPDRLE EEHRRGLTIE LGYCWTELPG LGEVAFVDVP
     GHERFVSTML AGIGPVPAVL FVVAADDPWM PQAAEHLAAL DSLGVGHGVV AVTRSDLADP
     APMVARVTDE LARTSLRGSP VVPVSGRTGA GLDELRGRLA TMLRGLPPVD PSDDVRLWVD
     RRFTIKGAGT VVTGTLPSGT VSRGDTLSVG GARVRVRGVQ SLGRTVPAAT GVARVALNLV
     GEDLSGLERG AALVSAGAWH RTDVLDVRLS GAATGPPERP MFHVGATAVG AHCRPLADDL
     VRLTLDAPLP LRVGDKALLR DPGDRRLWGV TVLDPAPPSL RRRGASRQRA AVLAPLTGAP
     DLASEVQRRE VATVDLLRRI GVPVRQPPPG AVLADGWLMS ADRADAAAAA LAEAVARHAA
     AAPLDQALSV GALADAVGLP SPALVEAVVR PPLRVERGRV VAPRATTGLP PALEAAVDAV
     EEDLRDQPFA APTADRLAEL GLDARAVAAA VRAGRLLRVA PGIVLRPGAE RTAVAWLAEL
     EQPFTASQAR GRLGTTRRVV LPLLDHLDRS GLTRRLPDDR RTVV
//