ID   A0A7H9HUN4_9SACH        Unreviewed;       335 AA.
AC   A0A7H9HUN4;
DT   10-FEB-2021, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2021, sequence version 1.
DT   08-OCT-2025, entry version 19.
DE   RecName: Full=GDP-mannose transporter {ECO:0000256|RuleBase:RU367097};
DE            Short=GMT {ECO:0000256|RuleBase:RU367097};
GN   ORFNames=HG537_0D00620 {ECO:0000313|EMBL:QLQ80062.1};
OS   Torulaspora globosa.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Torulaspora.
OX   NCBI_TaxID=48254 {ECO:0000313|EMBL:QLQ80062.1, ECO:0000313|Proteomes:UP000510647};
RN   [1] {ECO:0000313|EMBL:QLQ80062.1, ECO:0000313|Proteomes:UP000510647}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS2947 {ECO:0000313|EMBL:QLQ80062.1,
RC   ECO:0000313|Proteomes:UP000510647};
RA   Coughlan A.Y., Lombardi L., Braun-Galleani S., Martos A.R., Galeote V.,
RA   Bigey F., Dequin S., Byrne K.P., Wolfe K.H.;
RT   "The yeast mating-type switching endonuclease HO is a domesticated member
RT   of an unorthodox homing genetic element family.";
RL   Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the import of GDP-mannose from the cytoplasm into
CC       the Golgi lumen. {ECO:0000256|RuleBase:RU367097}.
CC   -!- SUBUNIT: Homooligomer. {ECO:0000256|RuleBase:RU367097}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC       {ECO:0000256|ARBA:ARBA00004439, ECO:0000256|RuleBase:RU367097}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004439,
CC       ECO:0000256|RuleBase:RU367097}. Golgi apparatus membrane
CC       {ECO:0000256|RuleBase:RU367097}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU367097}. Endoplasmic reticulum membrane
CC       {ECO:0000256|RuleBase:RU367097}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU367097}.
CC   -!- SIMILARITY: Belongs to the TPT transporter family. SLC35D subfamily.
CC       {ECO:0000256|RuleBase:RU367097}.
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DR   EMBL; CP059270; QLQ80062.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A7H9HUN4; -.
DR   OrthoDB; 417037at2759; -.
DR   Proteomes; UP000510647; Chromosome 4.
DR   GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR013657; SCL35B1-4/HUT1.
DR   InterPro; IPR050186; TPT_transporter.
DR   NCBIfam; TIGR00803; nst; 1.
DR   PANTHER; PTHR11132; SOLUTE CARRIER FAMILY 35; 1.
DR   Pfam; PF08449; UAA; 1.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE   3: Inferred from homology;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329,
KW   ECO:0000256|RuleBase:RU367097};
KW   Endoplasmic reticulum {ECO:0000256|RuleBase:RU367097};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW   ECO:0000256|RuleBase:RU367097};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU367097};
KW   Reference proteome {ECO:0000313|Proteomes:UP000510647};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW   ECO:0000256|RuleBase:RU367097};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU367097};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU367097};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU367097}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        86..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        115..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        141..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        177..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        252..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        278..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        304..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
SQ   SEQUENCE   335 AA;  36844 MW;  4A833DC40D328FEA CRC64;
     MSELKISANE NAWSRVANSG SISILSYCGS SILMTVTNKF VVNLKDFNMN LVMLFVQSLV
     CTLTLVVLKF LGYAKFRPLN KTDAKNWLPI SILLVLMIYT SSKALQFLAV PIYTIFKNLT
     IILIAYGEVL FFGGSITSME LSSFLLMVLS SVIATWGDQQ ALAKKAAQTA VLGESALPFS
     IGYLWMFANC ISSALFVLIM RKRIKLTNFK DFDTMFYNNV LGMPILLVAS FIVEDWSQAN
     LATNLSQDSV TAMIISGLAS VGISYCSGWC VRVTSSTTYS MVGALNKLPI ALSGLIFFDA
     PRNFLSFLSI FIGFLSGIVY AVAKQKKMQN QASQK
//