ID A0A7J5XMC8_DISMA Unreviewed; 902 AA.
AC A0A7J5XMC8;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 18-JUN-2025, entry version 19.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN ORFNames=F7725_010024 {ECO:0000313|EMBL:KAF3838256.1};
OS Dissostichus mawsoni (Antarctic cod).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Notothenioidei; Nototheniidae; Dissostichus.
OX NCBI_TaxID=36200 {ECO:0000313|EMBL:KAF3838256.1, ECO:0000313|Proteomes:UP000518266};
RN [1] {ECO:0000313|EMBL:KAF3838256.1, ECO:0000313|Proteomes:UP000518266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DM0001 {ECO:0000313|EMBL:KAF3838256.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAF3838256.1};
RA Park H.;
RT "Dissostichus mawsoni Genome sequencing and assembly.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. SIGLEC (sialic
CC acid binding Ig-like lectin) family. {ECO:0000256|ARBA:ARBA00038361}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF3838256.1}.
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DR EMBL; JAAKFY010000022; KAF3838256.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7J5XMC8; -.
DR OrthoDB; 9936425at2759; -.
DR Proteomes; UP000518266; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0033691; F:sialic acid binding; IEA:TreeGrafter.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR051036; SIGLEC.
DR PANTHER; PTHR12035; SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN; 1.
DR PANTHER; PTHR12035:SF125; SIALIC ACID-BINDING IG-LIKE LECTIN 5; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF25305; Ig_PDGFR_d4; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Lectin {ECO:0000256|ARBA:ARBA00022734};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000518266};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 600..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 293..386
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 421..481
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 68..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 791..817
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 836..902
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..805
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 902 AA; 100500 MW; B03001D68E516AC0 CRC64;
MLMRIIAIQS VGSCPEMKLY GVNDPPPAGV GVPLSSGEEK LACAALLGLD PGKLYAYSSR
GAYMELQAPV DGSPTPGTRR GPNAGRQTPR TEREVYTCRI TLKSRQAAAS HPQPENTGPL
QDNSWRKIKC SECFYHEEGD GIHASSDALL YFCTELRCVE ISPDDKELTL AEGSFLSLTC
SGSGETTWEF KSVDVPYCQV EQFQNDPKVW FIERSHGMVT KNSEESTVPC VVSNPDINVT
LYERDTDQPI RGLYVPSEGY KAPLEERTYV CRGEMNGEVM ESQAFYVFSV TIPEAIDIYI
NASNTVLKQG EPLTVNCTVQ GMEIADFSWD RPNSEDVEPL TDVLPNTNMR SCLIFPHAMV
ANSGNYVCHV HEPVLDQTAS ASVNITVLER GFVDVKAAQK QNISARLQEN VQLRVDIEAY
PPPQVRWSKD GATIKGHKPI TTRQEHEIRY VTILTLVRVR TEQKGLYSVL VTNGDDTKEV
TFDLEIKYLT DHHLPGKKHL VTCVAEGVPV PSIQWYSCDS MHKCSNQTEV WQPLIAEPEV
VSIRTNVSYS DTRKTSQVRS QVTFHKPQQV TVRCETSNRA GLLDRRDVNW CPNTALYSQV
AVLAAVLALV VIIIISIIIL VAVWRKYCRY GDLVDYLHRN KHSLLQNYAE KNQDESCLIS
GGSTPLSQRK GESDGGYMDM SKDEPSIYMP MQEHMDTIKY ADIQPSPYES PYQHDIYQEQ
GGSRLDLFIS DSSALTYDDL LGFSYQVAKG MEFLASKNKY NQVNDSFLKS DHPAVTRTKP
RLSSPFPIAN PAFGSPPPHY VPPDPYTQSP SPGEFREEAD TQEVVTAYNE YIIPIPDPKP
DDVFTDVTSE SPASSLALEE EADSMSQDTA DTLPEEDRPE DTSERDALLG CSGTPEVEDS
FL
//
