ID   A0A7J5Y0H9_DISMA        Unreviewed;       670 AA.
AC   A0A7J5Y0H9;
DT   07-APR-2021, integrated into UniProtKB/TrEMBL.
DT   07-APR-2021, sequence version 1.
DT   18-JUN-2025, entry version 16.
DE   RecName: Full=Collagenase NC10/endostatin domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=F7725_001689 {ECO:0000313|EMBL:KAF3842840.1};
OS   Dissostichus mawsoni (Antarctic cod).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Notothenioidei; Nototheniidae; Dissostichus.
OX   NCBI_TaxID=36200 {ECO:0000313|EMBL:KAF3842840.1, ECO:0000313|Proteomes:UP000518266};
RN   [1] {ECO:0000313|EMBL:KAF3842840.1, ECO:0000313|Proteomes:UP000518266}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DM0001 {ECO:0000313|EMBL:KAF3842840.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:KAF3842840.1};
RA   Park H.;
RT   "Dissostichus mawsoni Genome sequencing and assembly.";
RL   Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KAF3842840.1}.
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DR   EMBL; JAAKFY010000018; KAF3842840.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A7J5Y0H9; -.
DR   OrthoDB; 10060752at2759; -.
DR   Proteomes; UP000518266; Unassembled WGS sequence.
DR   GO; GO:0031012; C:extracellular matrix; IEA:TreeGrafter.
DR   GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR   GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IEA:TreeGrafter.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:TreeGrafter.
DR   CDD; cd00247; Endostatin-like; 1.
DR   FunFam; 3.10.100.10:FF:000008; collagen alpha-1(XVIII) chain isoform X1; 1.
DR   FunFam; 3.40.1620.70:FF:000003; Collagen type XVIII alpha 1; 1.
DR   Gene3D; 3.40.1620.70; -; 1.
DR   Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR   InterPro; IPR016186; C-type_lectin-like/link_sf.
DR   InterPro; IPR050149; Collagen_superfamily.
DR   InterPro; IPR010515; Collagenase_NC10/endostatin.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR   PANTHER; PTHR24023:SF1112; COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR   Pfam; PF20010; Collagen_trimer; 1.
DR   Pfam; PF06482; Endostatin; 1.
DR   SUPFAM; SSF56436; C-type lectin-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000518266}.
FT   DOMAIN          376..422
FT                   /note="Collagen type XV/XVIII trimerization"
FT                   /evidence="ECO:0000259|Pfam:PF20010"
FT   DOMAIN          496..664
FT                   /note="Collagenase NC10/endostatin"
FT                   /evidence="ECO:0000259|Pfam:PF06482"
FT   REGION          18..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          183..210
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          273..345
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          450..483
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        288..305
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        469..479
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   670 AA;  73276 MW;  4B4502E19989C155 CRC64;
     MPPYRGLEET QGYRVFQDRP DWLVCPDPSD QSDSRGLPGP LDPATASDLM TWRPLVEVSA
     TDFLVPEDLK EDRVNLGCLV SPVRRAVKGP SEETDSPGWT ASPDLRDQRV TVVTKETGVS
     QVGMDPDSLA PPAHLDPRDK SSTRLMAMLV MLGGRVLLGQ GVTEENRGEK GEPGLVIGPD
     GSLLHLDGLS GQKGPYGPSG IKGEFGMPGR PGRPGVNGYK GEKGDTSGGS GYGYPCLANQ
     DNPDHLDPPD QPSPLIASIA MTTVQGITQQ LKETKESKVT MDCQESQNEL KGERGDVGVK
     GEKGEQIGGY YDQRFGGVQG QSGPPGSKGR LCNGTSWTPG ATRNPRDWLR WASSRQYSWT
     SRPPGQPGSP ALSSGVTVLR SYETMVATAR RQSEGSLIYI IDKADLYLRV RDGLRQVMLG
     DYNPFFRDLE NEVAEVQPPP VIVYPDTQDQ SQNNGAGHYS HGGPVIRPIE PPPQPPVKPD
     TPHSMIPDSQ TRDRQLHIIA LNAPQTGNMR GIRGADFLCF QQARAVGLKG TFRAFLSSKL
     QDLYTIVRRA DRDNFSIVNL KDQVLFDSWE SMFGDNTNKM RENVPIYSFD GRDTLRDSAW
     PEKMVWHGSN NKGHRQTDHY CETWRTGDHA VSGLASSLQS GQLLQQSSSS CSGSYIVLCI
     ENAFTTHSKK
//