ID A0A7J5ZSK4_AMEME Unreviewed; 620 AA.
AC A0A7J5ZSK4;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 08-OCT-2025, entry version 13.
DE RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN ORFNames=AMELA_G00245730 {ECO:0000313|EMBL:KAF4073642.1};
OS Ameiurus melas (Black bullhead) (Silurus melas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ameiurus.
OX NCBI_TaxID=219545 {ECO:0000313|EMBL:KAF4073642.1, ECO:0000313|Proteomes:UP000593565};
RN [1] {ECO:0000313|EMBL:KAF4073642.1, ECO:0000313|Proteomes:UP000593565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M_S1 {ECO:0000313|EMBL:KAF4073642.1};
RC TISSUE=Blood {ECO:0000313|EMBL:KAF4073642.1};
RA Wen M., Zham M., Cabau C., Klopp C., Donnadieu C., Roques C., Bouchez O.,
RA Lampietro C., Jouanno E., Herpin A., Louis A., Berthelot C., Parey E.,
RA Roest-Crollius H., Braasch I., Postlethwait J., Robinson-Rechavi M.,
RA Echchiki A., Begum T., Montfort J., Schartl M., Bobe J., Guiguen Y.;
RT "A chromosome-scale genome assembly of the black bullhead catfish (Ameiurus
RT melas).";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF4073642.1}.
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DR EMBL; JAAGNN010000023; KAF4073642.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7J5ZSK4; -.
DR OrthoDB; 8933073at2759; -.
DR Proteomes; UP000593565; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR InterPro; IPR039363; ZNF750.
DR InterPro; IPR039064; ZNF750_Znf.
DR PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR Pfam; PF15269; zf-C2H2_7; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000593565};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 5..58
FT /note="Zinc finger protein 750-like zinc finger"
FT /evidence="ECO:0000259|Pfam:PF15269"
FT REGION 60..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 115..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..133
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..339
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..392
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..441
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..480
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 620 AA; 68981 MW; D3D1D23ADFB877F7 CRC64;
METRQERKPK KPHYIPRPPG KPFKYQCFQC PFTCNIKSHL FNHMKYNLCK NSISLVSQRG
EQTGRASRVP QRSTSSNQVV HTEPSIPAKP GPIRPDHPNG KMRIVEKLDE LAIREVEGGD
NREGNESPVK KVTESSTEPI SSESKDPGTV ETMIKCTSSS AFSPVQRKGE NVDGQPPRKA
DQPSSLVPVR PSFHPLPTWG QRAISAPLKA PADYPPYMLP ERTTHAFYQT YLQNQSIPPA
YCLSLQEHNR PLVPAPLIPP SHPSLLHPYP YRYSHPFLQV PPLPYGVYPP EHVPSLQSQR
YIPMEMFAHG FEPRDYGRYF YHQPGSYSRP SEARGNQQHG GDRATRQSPM AGCAASGSPD
RPSVTDINQH HPINPQHSAL RETQPTYQSD CTTKGRGPVT EPERLLRNLC TKQQDSSTQK
QRSSVRCSGL SEEAEDEDSD DTAAPLNLSK RGQNRSVCTP DHISDEEIES ESESGDEDAP
LDLCLRDQSN NPVQTGATTS SEGVPEQVGV GQDQTISSEQ EQCDRRHSAA FALCQLASSS
NINTTEHPSE PHTDTQSPSY QQRPAPDQAP NGDTTDTERS EQNSAARGKK RASDEVTKTT
GKRARANVLV RDKRRRTQNC
//
