ID A0A7J6B361_AMEME Unreviewed; 700 AA.
AC A0A7J6B361;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 13.
DE RecName: Full=Xenotropic and polytropic retrovirus receptor 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMELA_G00067920 {ECO:0000313|EMBL:KAF4089542.1};
OS Ameiurus melas (Black bullhead) (Silurus melas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ameiurus.
OX NCBI_TaxID=219545 {ECO:0000313|EMBL:KAF4089542.1, ECO:0000313|Proteomes:UP000593565};
RN [1] {ECO:0000313|EMBL:KAF4089542.1, ECO:0000313|Proteomes:UP000593565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M_S1 {ECO:0000313|EMBL:KAF4089542.1};
RC TISSUE=Blood {ECO:0000313|EMBL:KAF4089542.1};
RA Wen M., Zham M., Cabau C., Klopp C., Donnadieu C., Roques C., Bouchez O.,
RA Lampietro C., Jouanno E., Herpin A., Louis A., Berthelot C., Parey E.,
RA Roest-Crollius H., Braasch I., Postlethwait J., Robinson-Rechavi M.,
RA Echchiki A., Begum T., Montfort J., Schartl M., Bobe J., Guiguen Y.;
RT "A chromosome-scale genome assembly of the black bullhead catfish (Ameiurus
RT melas).";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF4089542.1}.
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DR EMBL; JAAGNN010000005; KAF4089542.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7J6B361; -.
DR OrthoDB; 9970435at2759; -.
DR Proteomes; UP000593565; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:TreeGrafter.
DR GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter.
DR GO; GO:0000822; F:inositol hexakisphosphate binding; IEA:TreeGrafter.
DR GO; GO:0016036; P:cellular response to phosphate starvation; IEA:TreeGrafter.
DR GO; GO:0006817; P:phosphate ion transport; IEA:TreeGrafter.
DR CDD; cd14477; SPX_XPR1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF135; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1 HOMOLOG; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 1.
DR Pfam; PF03105; SPX; 2.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000593565};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 237..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 515..536
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..177
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 445..649
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
FT REGION 656..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 70..97
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 700 AA; 81481 MW; 8B80A799623F4C93 CRC64;
MKFTEHLAAH ITPEWRKQYI QYEAFKEMLY SAQDQAPSIE VTDDDTVKRY YAKFEEKFFQ
TCEKELAKIN TFYSEKLAEA QRRFATLQNE LQSSLDAQRE SSRAPGLRAR RRAVFHLSQQ
ERCKHSNIKD LQLAFSEFYL SLILLQNYQN LNFTGFRKIL KKHDKIFETV RGADWRVAHV
EVAPFYTCKK ITQLISETET LVTTELEGGD RQKAMKRLRV PPLGAAQPAP AWTTFRVGLY
CGVFIVLIVT ISVTGIAKRM QSSEMPSSVW PLVRIYRGGF LLIEFLFLLG INTYGWRQAG
VNHVLIFELN PRNNLSHQHL FEIAGFLGML WCVSILSCLF SDSLKIPIQA CPLALYGFFL
LFLINPFKTC YYKSRFWLLK LLFRVVTAPF HRVGFADFWL ADQLNSLAVV LMDLEYLICF
YSVELDWLTS YDKLEINSAN PLRNTCNTYS YGVRAIIQCL PAWFRFVQCL RRYRDTKRAF
PHLVNAGKYS TTFFVVTFAA LYKTHKADKH SDTDMFLYLL IACSIINSCY TLIWDLKMDW
GLFDRNAGEN ALLREEIVYP QKAYYYCAIL EDVMLRFAWT IPLSLGVLTS EPFISDILAT
VLAPLEVFRR FVWNFFRLEN EHLNNCGEFR AVRDISVAPL NADDQTLLEQ MMDQEDGVRN
RQGKKSWKRS YSMSLKRPRL ASQSKLRDTK VLIEDTDDDT
//
