ID A0A7J7ZU59_MYOMY Unreviewed; 573 AA.
AC A0A7J7ZU59;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 08-OCT-2025, entry version 14.
DE SubName: Full=Collagen type XVIII alpha 1 chain {ECO:0000313|EMBL:KAF6377619.1};
GN ORFNames=mMyoMyo1_003131 {ECO:0000313|EMBL:KAF6377619.1};
OS Myotis myotis (Greater mouse-eared bat) (Vespertilio myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=51298 {ECO:0000313|EMBL:KAF6377619.1, ECO:0000313|Proteomes:UP000527355};
RN [1] {ECO:0000313|EMBL:KAF6377619.1, ECO:0000313|Proteomes:UP000527355}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMyoMyo1 {ECO:0000313|EMBL:KAF6377619.1};
RC TISSUE=Flight muscle {ECO:0000313|EMBL:KAF6377619.1};
RX PubMed=32699395;
RA Jebb D., Huang Z., Pippel M., Hughes G.M., Lavrichenko K., Devanna P.,
RA Winkler S., Jermiin L.S., Skirmuntt E.C., Katzourakis A., Burkitt-Gray L.,
RA Ray D.A., Sullivan K.A.M., Roscito J.G., Kirilenko B.M., Davalos L.M.,
RA Corthals A.P., Power M.L., Jones G., Ransome R.D., Dechmann D.K.N.,
RA Locatelli A.G., Puechmaille S.J., Fedrigo O., Jarvis E.D., Hiller M.,
RA Vernes S.C., Myers E.W., Teeling E.C.;
RT "Six reference-quality genomes reveal evolution of bat adaptations.";
RL Nature 583:578-584(2020).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF6377619.1}.
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DR EMBL; JABWUV010000002; KAF6377619.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7J7ZU59; -.
DR VEuPathDB; HostDB:GeneID_118676132; -.
DR Proteomes; UP000527355; Unassembled WGS sequence.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0031012; C:extracellular matrix; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IEA:TreeGrafter.
DR GO; GO:0032836; P:glomerular basement membrane development; IEA:TreeGrafter.
DR CDD; cd00247; Endostatin-like; 1.
DR FunFam; 3.10.100.10:FF:000008; collagen alpha-1(XVIII) chain isoform X1; 1.
DR FunFam; 3.40.1620.70:FF:000003; Collagen type XVIII alpha 1; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF714; COLLAGEN ALPHA-4(IV) CHAIN; 1.
DR Pfam; PF01391; Collagen; 1.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119, ECO:0000313|EMBL:KAF6377619.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000527355}.
FT DOMAIN 264..312
FT /note="Collagen type XV/XVIII trimerization"
FT /evidence="ECO:0000259|Pfam:PF20010"
FT DOMAIN 400..569
FT /note="Collagenase NC10/endostatin"
FT /evidence="ECO:0000259|Pfam:PF06482"
FT REGION 1..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..88
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..174
FT /note="Gly residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..187
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..233
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..255
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 573 AA; 60115 MW; 819A4A22790D8BDE CRC64;
MVFSPDGRVL PPAQKGAKGE PGFRGPPGPY GRPGHKGEIG FPGRPGRPGM NGFKGEKGEP
GDASVGFGAR GPPGLPGPPG PPGPPGLPGN PVYDTNAFVE SGPVGPPGLP GHQGPSGPKG
DKGEVGPPGP PGQFPFDFLQ LEAELKGDKG DRGDTGQKGE RGEPGGGGFF GSGVPGPPGP
PGYPGIPGPK GESIRGQPGP PGPQGPPGIG YEGRQGPPGP PGPPGPPGPP SFPGPYRQTI
SIPGPPGPPG PPGPPGTLGT SSGVRIWPTY QTMLDKVPEV PEGWLIFVAD REELYVRVRN
GIRKVLLEAR TPLPRGTDNE VAALQPPLVQ LHEGNPHPRW ELPPSTSRPW RADDILVRPP
RLLDPQPYPG VPHHGSYVHS RPAHPTGAPA HTHHDFQPVL HLVALNGPQP GGLRGIRGAD
LQCFQQARAA GLAGTFRAFL SSRLQDLYSI VRRADRATVP IVNLRDEELF PNWEALFSGS
QGQLKPGARI FSFDGRDVLQ HPAWPQKSVW HGSDPSGRRL TESYCETWRT EATTATGQAS
SMLTGRLLGQ KAVSCHNAFI VLCIENSFMT SSK
//
