ID A0A7J7ZUU1_MYOMY Unreviewed; 727 AA.
AC A0A7J7ZUU1;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 15.
DE SubName: Full=Collagen type XVIII alpha 1 chain {ECO:0000313|EMBL:KAF6377616.1};
GN ORFNames=mMyoMyo1_003131 {ECO:0000313|EMBL:KAF6377616.1};
OS Myotis myotis (Greater mouse-eared bat) (Vespertilio myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=51298 {ECO:0000313|EMBL:KAF6377616.1, ECO:0000313|Proteomes:UP000527355};
RN [1] {ECO:0000313|EMBL:KAF6377616.1, ECO:0000313|Proteomes:UP000527355}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMyoMyo1 {ECO:0000313|EMBL:KAF6377616.1};
RC TISSUE=Flight muscle {ECO:0000313|EMBL:KAF6377616.1};
RX PubMed=32699395;
RA Jebb D., Huang Z., Pippel M., Hughes G.M., Lavrichenko K., Devanna P.,
RA Winkler S., Jermiin L.S., Skirmuntt E.C., Katzourakis A., Burkitt-Gray L.,
RA Ray D.A., Sullivan K.A.M., Roscito J.G., Kirilenko B.M., Davalos L.M.,
RA Corthals A.P., Power M.L., Jones G., Ransome R.D., Dechmann D.K.N.,
RA Locatelli A.G., Puechmaille S.J., Fedrigo O., Jarvis E.D., Hiller M.,
RA Vernes S.C., Myers E.W., Teeling E.C.;
RT "Six reference-quality genomes reveal evolution of bat adaptations.";
RL Nature 583:578-584(2020).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF6377616.1}.
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DR EMBL; JABWUV010000002; KAF6377616.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7J7ZUU1; -.
DR VEuPathDB; HostDB:GeneID_118676132; -.
DR Proteomes; UP000527355; Unassembled WGS sequence.
DR GO; GO:0005594; C:collagen type IX trimer; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IEA:TreeGrafter.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:TreeGrafter.
DR CDD; cd00247; Endostatin-like; 1.
DR FunFam; 3.10.100.10:FF:000008; collagen alpha-1(XVIII) chain isoform X1; 1.
DR FunFam; 3.40.1620.70:FF:000003; Collagen type XVIII alpha 1; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF1116; MACROPHAGE RECEPTOR WITH COLLAGENOUS STRUCTURE; 1.
DR Pfam; PF01391; Collagen; 2.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119, ECO:0000313|EMBL:KAF6377616.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000527355}.
FT DOMAIN 418..466
FT /note="Collagen type XV/XVIII trimerization"
FT /evidence="ECO:0000259|Pfam:PF20010"
FT DOMAIN 554..723
FT /note="Collagenase NC10/endostatin"
FT /evidence="ECO:0000259|Pfam:PF06482"
FT REGION 1..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 115..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..37
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..81
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..96
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..242
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..317
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..328
FT /note="Gly residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..341
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..387
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..409
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 727 AA; 74581 MW; 597DBD190A223DDA CRC64;
MEGSGGPFWL TARGADGLQG PPGKPGAKGD PGIAGPPGTK GEVGADGPPG FPGLPGKEGV
AGAQGPKGEK GTQGEKGDPG KDGVGQPGPP GPPGLPGPVV YVSEEQDRAV SVTHGVKGQP
GYAGLPGPAG PKGDTGVSGQ PGPPGPKGEK GEPGMVFSPD GRVLPPAQKG AKGEPGFRGP
PGPYGRPGHK GEIGFPGRPG RPGMNGFKGE KGEPGDASVG FGARGPPGLP GPPGPPGPPG
LPGNPVYDTN AFVESGPVGP PGLPGHQGPS GPKGDKGEVG PPGPPGQFPF DFLQLEAELK
GDKGDRGDTG QKGERGEPGG GGFFGSGVPG PPGPPGYPGI PGPKGESIRG QPGPPGPQGP
PGIGYEGRQG PPGPPGPPGP PGPPSFPGPY RQTISIPGPP GPPGPPGPPG TLGTSSGVRI
WPTYQTMLDK VPEVPEGWLI FVADREELYV RVRNGIRKVL LEARTPLPRG TDNEVAALQP
PLVQLHEGNP HPRWELPPST SRPWRADDIL VRPPRLLDPQ PYPGVPHHGS YVHSRPAHPT
GAPAHTHHDF QPVLHLVALN GPQPGGLRGI RGADLQCFQQ ARAAGLAGTF RAFLSSRLQD
LYSIVRRADR ATVPIVNLRD EELFPNWEAL FSGSQGQLKP GARIFSFDGR DVLQHPAWPQ
KSVWHGSDPS GRRLTESYCE TWRTEATTAT GQASSMLTGR LLGQKAVSCH NAFIVLCIEN
SFMTSSK
//
