ID A0A7J8B6X0_MOLMO Unreviewed; 436 AA.
AC A0A7J8B6X0;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 05-FEB-2025, entry version 11.
DE SubName: Full=Anomalous homeobox {ECO:0000313|EMBL:KAF6394444.1};
GN ORFNames=HJG59_000687 {ECO:0000313|EMBL:KAF6394444.1};
OS Molossus molossus (Pallas' mastiff bat) (Vespertilio molossus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Molossidae;
OC Molossus.
OX NCBI_TaxID=27622 {ECO:0000313|EMBL:KAF6394444.1, ECO:0000313|Proteomes:UP000550707};
RN [1] {ECO:0000313|EMBL:KAF6394444.1, ECO:0000313|Proteomes:UP000550707}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMolMol1 {ECO:0000313|EMBL:KAF6394444.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAF6394444.1};
RX PubMed=32699395;
RA Jebb D., Huang Z., Pippel M., Hughes G.M., Lavrichenko K., Devanna P.,
RA Winkler S., Jermiin L.S., Skirmuntt E.C., Katzourakis A., Burkitt-Gray L.,
RA Ray D.A., Sullivan K.A.M., Roscito J.G., Kirilenko B.M., Davalos L.M.,
RA Corthals A.P., Power M.L., Jones G., Ransome R.D., Dechmann D.K.N.,
RA Locatelli A.G., Puechmaille S.J., Fedrigo O., Jarvis E.D., Hiller M.,
RA Vernes S.C., Myers E.W., Teeling E.C.;
RT "Six reference-quality genomes reveal evolution of bat adaptations.";
RL Nature 583:578-584(2020).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF6394444.1}.
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DR EMBL; JACASF010000053; KAF6394444.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7J8B6X0; -.
DR InParanoid; A0A7J8B6X0; -.
DR Proteomes; UP000550707; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:TreeGrafter.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0014857; P:regulation of skeletal muscle cell proliferation; IEA:TreeGrafter.
DR GO; GO:0048741; P:skeletal muscle fiber development; IEA:TreeGrafter.
DR CDD; cd00086; homeodomain; 1.
DR FunFam; 1.10.10.60:FF:000412; Anomalous homeobox; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR001356; HD.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR009057; Homeodomain-like_sf.
DR InterPro; IPR008422; KN_HD.
DR InterPro; IPR031701; SIX1_SD.
DR PANTHER; PTHR10390:SF34; ANOMALOUS HOMEOBOX PROTEIN; 1.
DR PANTHER; PTHR10390; HOMEOBOX PROTEIN SIX; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF16878; SIX1_SD; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000550707}.
FT DOMAIN 154..195
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 156..196
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 201..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 436 AA; 46964 MW; D256F3C327B44E8F CRC64;
MQSFLKLLRE SGGTNPPLEE LVTLAGRLCR DLQDDLTQVQ PLVTAVLESQ LRLYLLDNED
VALVCARVLA QQEQHQAACR LLEGCRVPGG SLELVQLWND IHYHVVMKRL GVATLTPVQK
FRCRKRNPPP PSLCPDGLKS RNFPRDIRQK LQDFAAGVSS NPSKAQREIL AAETSLTAEQ
VYNWFANYRR RQRAGLRRME LADSAEGPPQ PSGPHHPGFG CVRPPQWSGG EDSGPASSLV
TTQGLWEPLA LASDFSGEET IPKSLAPSNM LDPSSAAPKS WLTSLALASS RDVSFRTGQL
VHSHEVDFTM PPADTSMAVS VATLAEPSPT GFADPSSSDP RSTYLEEGLG TSLSQGEGQA
GSFLVPQPPL QAPEFILPQS LPELAPAPSA FPSPAPAVQL SEPLPSCQVP WPDSQASSDA
FWGARMLLEL SGGSLG
//
