ID A0A7J8EQ44_MOLMO Unreviewed; 431 AA.
AC A0A7J8EQ44;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 08-OCT-2025, entry version 13.
DE SubName: Full=Chordin like 2 {ECO:0000313|EMBL:KAF6437249.1};
GN ORFNames=HJG59_002846 {ECO:0000313|EMBL:KAF6437249.1};
OS Molossus molossus (Pallas' mastiff bat) (Vespertilio molossus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Molossidae;
OC Molossus.
OX NCBI_TaxID=27622 {ECO:0000313|EMBL:KAF6437249.1, ECO:0000313|Proteomes:UP000550707};
RN [1] {ECO:0000313|EMBL:KAF6437249.1, ECO:0000313|Proteomes:UP000550707}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMolMol1 {ECO:0000313|EMBL:KAF6437249.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAF6437249.1};
RX PubMed=32699395;
RA Jebb D., Huang Z., Pippel M., Hughes G.M., Lavrichenko K., Devanna P.,
RA Winkler S., Jermiin L.S., Skirmuntt E.C., Katzourakis A., Burkitt-Gray L.,
RA Ray D.A., Sullivan K.A.M., Roscito J.G., Kirilenko B.M., Davalos L.M.,
RA Corthals A.P., Power M.L., Jones G., Ransome R.D., Dechmann D.K.N.,
RA Locatelli A.G., Puechmaille S.J., Fedrigo O., Jarvis E.D., Hiller M.,
RA Vernes S.C., Myers E.W., Teeling E.C.;
RT "Six reference-quality genomes reveal evolution of bat adaptations.";
RL Nature 583:578-584(2020).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF6437249.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JACASF010000013; KAF6437249.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7J8EQ44; -.
DR Proteomes; UP000550707; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0036122; F:BMP binding; IEA:TreeGrafter.
DR GO; GO:0030154; P:cell differentiation; IEA:TreeGrafter.
DR GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:TreeGrafter.
DR GO; GO:0048731; P:system development; IEA:UniProtKB-ARBA.
DR FunFam; 2.10.70.10:FF:000005; Chordin-like 1, isoform CRA_c; 2.
DR Gene3D; 6.20.200.20; -; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 2.
DR InterPro; IPR045717; CHRDL1/2.
DR InterPro; IPR045716; CHRDL_1/2_C.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR46303:SF3; CHORDIN-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR46303; VWFC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF19548; CHRDL_1_2_C; 1.
DR Pfam; PF00093; VWC; 3.
DR SMART; SM00214; VWC; 3.
DR SUPFAM; SSF57603; FnI-like domain; 3.
DR PROSITE; PS01208; VWFC_1; 2.
DR PROSITE; PS50184; VWFC_2; 3.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000550707};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 32..97
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 110..176
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 251..316
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT REGION 183..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 431 AA; 47383 MW; 4F7EFDACB83A37DB CRC64;
MVMGTVVAGG LLGLRDGLPG PPHSELLPGP DVFCLFHGKR YSPGESWHPY LEPQGLMYCL
RCTCSESAHV NCYRLHCPPV YCPQPVTEPQ QCCPRCVEPH TPSGLRAPPK SCQHNGTMYQ
HGEMFSAHEL FPSRLPNQCV LCSCTEGQIY CGLMTCPEPG CPAPLPLPSS CCQACKDGSS
EKSAEEDTTQ SHRGVRHSQD LCSGDGVRKR GLGTPAPTGL SSPLGFIPRH FRPKGAGSTT
VKIVLKEKHK KACVHGGKTY SHGEVWHPAF RSFGPLPCIL CTCQDGHQDC QRVTCPTEYP
CHHPEKVAGK CCKICPEDKA DPGHSEISAT RCPKAPGRVL VHTSVSPSPD NLRRFALERE
ASEQVDIYLW KLVKGIFHLI QIKKVRKQDF QREAQNFRLL TGTHEGHWNV FLAQTPELKV
MASPDKGTKT L
//
