ID A0A7J8G0G2_MOLMO Unreviewed; 447 AA.
AC A0A7J8G0G2;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 18-JUN-2025, entry version 13.
DE SubName: Full=Polyhomeotic-like protein 1 {ECO:0000313|EMBL:KAF6453430.1};
GN ORFNames=HJG59_014136 {ECO:0000313|EMBL:KAF6453430.1};
OS Molossus molossus (Pallas' mastiff bat) (Vespertilio molossus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Molossidae;
OC Molossus.
OX NCBI_TaxID=27622 {ECO:0000313|EMBL:KAF6453430.1, ECO:0000313|Proteomes:UP000550707};
RN [1] {ECO:0000313|EMBL:KAF6453430.1, ECO:0000313|Proteomes:UP000550707}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMolMol1 {ECO:0000313|EMBL:KAF6453430.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAF6453430.1};
RX PubMed=32699395;
RA Jebb D., Huang Z., Pippel M., Hughes G.M., Lavrichenko K., Devanna P.,
RA Winkler S., Jermiin L.S., Skirmuntt E.C., Katzourakis A., Burkitt-Gray L.,
RA Ray D.A., Sullivan K.A.M., Roscito J.G., Kirilenko B.M., Davalos L.M.,
RA Corthals A.P., Power M.L., Jones G., Ransome R.D., Dechmann D.K.N.,
RA Locatelli A.G., Puechmaille S.J., Fedrigo O., Jarvis E.D., Hiller M.,
RA Vernes S.C., Myers E.W., Teeling E.C.;
RT "Six reference-quality genomes reveal evolution of bat adaptations.";
RL Nature 583:578-584(2020).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF6453430.1}.
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DR EMBL; JACASF010000010; KAF6453430.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7J8G0G2; -.
DR Proteomes; UP000550707; Unassembled WGS sequence.
DR GO; GO:0035102; C:PRC1 complex; IEA:TreeGrafter.
DR GO; GO:0003682; F:chromatin binding; IEA:TreeGrafter.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0042393; F:histone binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:TreeGrafter.
DR CDD; cd09577; SAM_Ph1_2_3; 1.
DR FunFam; 1.10.150.50:FF:000011; Polyhomeotic-like protein 2 isoform 1; 1.
DR FunFam; 3.30.60.160:FF:000002; Polyhomeotic-like protein 2 isoform 1; 1.
DR Gene3D; 3.30.60.160; -; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR050548; PcG_chromatin_remod_factors.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR012313; Znf_FCS.
DR InterPro; IPR038603; Znf_FCS_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF20; POLYHOMEOTIC-LIKE PROTEIN 1; 1.
DR Pfam; PF16616; PHC2_SAM_assoc; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF21319; zf-FCS_1; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS51024; ZF_FCS; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000550707};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00367}.
FT DOMAIN 234..268
FT /note="FCS-type"
FT /evidence="ECO:0000259|PROSITE:PS51024"
FT DOMAIN 383..447
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 76..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..26
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 447 AA; 47932 MW; 7DB25D4612BE12AE CRC64;
MPGTMQPGQA HLASSPPSSQ APGALQECPS TLASGMTLAP VQGTAHVVKG GATTSSPVVA
QVPAAFYMQS VHLPGKPQTL GVKRKAESEE ERDDVSTLAS LLPAKASAVA ESPKAMEEKS
SLGEKVELVT NVNTNTPSSE LVSLAPAPSA PPPTLAMVSR QMGDSKPPQA IVKPQILTHI
IEGFVIQEGA EPFPVGCSQL LKESEKPLQT GLLTGLNENQ SCGPLGGDSP SAELDKKANL
LKCEYCGKYA PADQFRGSKR FCSMTCAKRY NVSCSHQFRL KRKKMKEFQE ANYARVRRRG
PRRSSSDIAR AKIQGKRHRG QEDSSRGSDN SSYDEALSPT SPGPLSVRAG HGERDLGNPN
TAPPTPELHG INPMFLSSNP SRWSVEEVYE FIASLQGCQE IAEEFRSQEI DGQALLLLKE
EHLMSAMNIK LGPALKICAK INVLKET
//
