ID A0A7J8GL63_MOLMO Unreviewed; 445 AA.
AC A0A7J8GL63;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 08-OCT-2025, entry version 14.
DE RecName: Full=Integrin beta-like protein 1 {ECO:0000256|ARBA:ARBA00068076};
GN ORFNames=HJG59_006980 {ECO:0000313|EMBL:KAF6460425.1};
OS Molossus molossus (Pallas' mastiff bat) (Vespertilio molossus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Molossidae;
OC Molossus.
OX NCBI_TaxID=27622 {ECO:0000313|EMBL:KAF6460425.1, ECO:0000313|Proteomes:UP000550707};
RN [1] {ECO:0000313|EMBL:KAF6460425.1, ECO:0000313|Proteomes:UP000550707}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMolMol1 {ECO:0000313|EMBL:KAF6460425.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAF6460425.1};
RX PubMed=32699395;
RA Jebb D., Huang Z., Pippel M., Hughes G.M., Lavrichenko K., Devanna P.,
RA Winkler S., Jermiin L.S., Skirmuntt E.C., Katzourakis A., Burkitt-Gray L.,
RA Ray D.A., Sullivan K.A.M., Roscito J.G., Kirilenko B.M., Davalos L.M.,
RA Corthals A.P., Power M.L., Jones G., Ransome R.D., Dechmann D.K.N.,
RA Locatelli A.G., Puechmaille S.J., Fedrigo O., Jarvis E.D., Hiller M.,
RA Vernes S.C., Myers E.W., Teeling E.C.;
RT "Six reference-quality genomes reveal evolution of bat adaptations.";
RL Nature 583:578-584(2020).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF6460425.1}.
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DR EMBL; JACASF010000009; KAF6460425.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7J8GL63; -.
DR Proteomes; UP000550707; Unassembled WGS sequence.
DR GO; GO:0009986; C:cell surface; IEA:TreeGrafter.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005925; C:focal adhesion; IEA:TreeGrafter.
DR GO; GO:0008305; C:integrin complex; IEA:TreeGrafter.
DR GO; GO:0005178; F:integrin binding; IEA:TreeGrafter.
DR GO; GO:0033627; P:cell adhesion mediated by integrin; IEA:TreeGrafter.
DR GO; GO:0016477; P:cell migration; IEA:TreeGrafter.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:TreeGrafter.
DR GO; GO:0007160; P:cell-matrix adhesion; IEA:TreeGrafter.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR FunFam; 2.10.25.10:FF:000249; Integrin subunit beta like 1; 1.
DR FunFam; 2.10.25.10:FF:000374; Integrin subunit beta like 1; 1.
DR FunFam; 2.10.25.10:FF:000384; Integrin subunit beta like 1; 1.
DR FunFam; 2.10.25.10:FF:000042; Integrin subunit beta-like 1; 4.
DR FunFam; 2.10.25.10:FF:000175; Integrin subunit beta-like 1; 1.
DR Gene3D; 2.10.25.10; Laminin; 9.
DR InterPro; IPR013111; EGF_extracell.
DR InterPro; IPR057073; EGF_integrin_2.
DR InterPro; IPR015812; Integrin_bsu.
DR InterPro; IPR057243; Integrin_I-EGF_CS.
DR PANTHER; PTHR10082; INTEGRIN BETA SUBUNIT; 1.
DR PANTHER; PTHR10082:SF3; INTEGRIN BETA-LIKE PROTEIN 1; 1.
DR Pfam; PF07974; EGF_2; 5.
DR Pfam; PF23105; EGF_integrin; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 6.
DR PROSITE; PS00243; I_EGF_1; 6.
DR PROSITE; PS52047; I_EGF_2; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000313|EMBL:KAF6460425.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000550707};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..445
FT /note="Integrin beta-like protein 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5029788182"
FT DOMAIN 46..90
FT /note="Integrin beta epidermal growth factor-like"
FT /evidence="ECO:0000259|Pfam:PF23105"
FT DOMAIN 136..167
FT /note="Epidermal growth factor-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
FT DOMAIN 236..261
FT /note="Epidermal growth factor-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
FT DOMAIN 278..312
FT /note="Epidermal growth factor-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
FT DOMAIN 319..349
FT /note="Epidermal growth factor-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
FT DOMAIN 406..436
FT /note="Epidermal growth factor-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
SQ SEQUENCE 445 AA; 48262 MW; 48B65208C728EA3B CRC64;
MPPAGFGNFL LLACPFLLAG LSAVPQNFSP SLRSGPGATC RLSRAESERR CRAPGQPPGG
ALCHGRGRCD CGVCICHVNE PGVYFGPLCE CHEWVCETYD GKTCAGTCHC GRCKCDNSDG
NGLVYGKFCE CDDRECIDDE TEEICGGHGK CYCGNCYCEA GWHGDKCEFQ CDITPWESKR
RCTSPDGKIC SNRGTCVCGE CSCHDVDPTG DWGDIHGDTC ECDERDCRAV YDRYSDDFCS
GHGQCNCGRC DCKAGWHGKK CEHPRSCPLS AEESIRKCQG GSDLPCSGRG KCECGKCTCY
PPGDRRVYGK TCECDDRRCE DLDGVVCGGH GTCSCGRCVC ERGWFGKLCQ HPRKCNVTEE
LSKSLCESAD GILCSGKGSC HCGKCICSAE EWYISGEFCD CDDRDCDKHD GLICTGNGIC
SCGNCECWDG WNGNACEIWL GTEYP
//
