ID A0A7J8I4Q3_MOLMO Unreviewed; 1164 AA.
AC A0A7J8I4Q3;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 18-JUN-2025, entry version 15.
DE SubName: Full=AF4/FMR2 family member 4 {ECO:0000313|EMBL:KAF6478982.1};
GN ORFNames=HJG59_000435 {ECO:0000313|EMBL:KAF6478982.1};
OS Molossus molossus (Pallas' mastiff bat) (Vespertilio molossus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Molossidae;
OC Molossus.
OX NCBI_TaxID=27622 {ECO:0000313|EMBL:KAF6478982.1, ECO:0000313|Proteomes:UP000550707};
RN [1] {ECO:0000313|EMBL:KAF6478982.1, ECO:0000313|Proteomes:UP000550707}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMolMol1 {ECO:0000313|EMBL:KAF6478982.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAF6478982.1};
RX PubMed=32699395;
RA Jebb D., Huang Z., Pippel M., Hughes G.M., Lavrichenko K., Devanna P.,
RA Winkler S., Jermiin L.S., Skirmuntt E.C., Katzourakis A., Burkitt-Gray L.,
RA Ray D.A., Sullivan K.A.M., Roscito J.G., Kirilenko B.M., Davalos L.M.,
RA Corthals A.P., Power M.L., Jones G., Ransome R.D., Dechmann D.K.N.,
RA Locatelli A.G., Puechmaille S.J., Fedrigo O., Jarvis E.D., Hiller M.,
RA Vernes S.C., Myers E.W., Teeling E.C.;
RT "Six reference-quality genomes reveal evolution of bat adaptations.";
RL Nature 583:578-584(2020).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the AF4 family. {ECO:0000256|ARBA:ARBA00007354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF6478982.1}.
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DR EMBL; JACASF010000004; KAF6478982.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7J8I4Q3; -.
DR FunCoup; A0A7J8I4Q3; 2767.
DR InParanoid; A0A7J8I4Q3; -.
DR OrthoDB; 6382204at2759; -.
DR Proteomes; UP000550707; Unassembled WGS sequence.
DR GO; GO:0032783; C:super elongation complex; IEA:TreeGrafter.
DR GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR Gene3D; 6.10.250.2670; -; 1.
DR InterPro; IPR007797; AF4/FMR2.
DR InterPro; IPR043640; AF4/FMR2_CHD.
DR InterPro; IPR043639; AF4_int.
DR PANTHER; PTHR10528; AF4/FMR2 FAMILY MEMBER; 1.
DR PANTHER; PTHR10528:SF15; AF4_FMR2 FAMILY MEMBER 4; 1.
DR Pfam; PF05110; AF-4; 1.
DR Pfam; PF18875; AF4_int; 1.
DR Pfam; PF18876; AFF4_CHD; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000550707}.
FT DOMAIN 899..1162
FT /note="AF4/FMR2 C-terminal homology"
FT /evidence="ECO:0000259|Pfam:PF18876"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 75..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1035..1074
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..194
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..217
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..252
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..413
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..430
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..463
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..561
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 569..587
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 600..613
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..628
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 731..762
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 770..790
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 800..812
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 837..863
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1063..1074
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1164 AA; 127625 MW; 97EA72136ED9EB75 CRC64;
MNREDRNVLR MKERERRNQE IQQGEDAFPP SSPLFAEPYK VTSKEDKLSS RIQSMLGNYD
EMKDFIGDRS IPKLVAIPKP TVPPTADEKS NPTFFEQRHG SSHQSSKWTP VGPAPSTSQS
QKRSSGLQSG HSSQRTSVGG SGGTNSSSQR HDRDSYSSSG SSSRKKGQHG SEHSKSRSSS
PGKPQAVSSL SSSHSRSHGN DHHSKEHQRS KSPRDPDANW DSPSRVPFSS GQHSSQSFPP
SLMSKSSSML QKPTAYVRPM DGQESMEPKL SSEHYSSQSH GNSMAELKPS SKAHLTKLKI
PSQPLDASAS GDVSCVDEIL KEMTHSWPPP LTAIHTPCKT EPSKFPFPTK ESQQSNFGPG
EQKRYNPSSK TSNGHQSKSM LKDDLKLSSS EDSDGEQDCD KTMPRSTPGS NSEPSHHNSE
GADNSRDDSS SHSGSESSSG SDSESETSSS DSEANEPSQS ASPEPEPPPT NKWQLDNWLN
KVNPHKVSPA SSVDSNIPSS QGYKKEGREQ GTGNNYTDPG GPKETSSATP GRDSKTAQKG
SESGRGRQKS PAQSDSTTQR RTVGKKQPKK VEKAAAEEPR GGLKIESETP VDMTTSMPSS
RHKAATKGSR KPNIKKESKS SPRPSAEKKK YKSTSKSSQK SREIIETDTS SSDSDESESL
PPSSQTPKYP ESNRTPIKPS SVEEEDSFFR QRMFSPMEEK ELLSPLSEPD DRYPLIVKID
LNLLTRIPGK PYKETEPPKG EKKNVPEKHT REAQKQASEK VSNKGKRKHK NEDDNRASES
KKPKTEDKNS AGHKPSSNRE SSKQSVAKEK DLLPSPAGPV PSKDPKTEHG SRKRTISQSS
SLKSSNNSNK ENSSSSKNSS STSKQKKTEG KTSSSSKEVK EKASNSSSNC PPSTPTPEAS
KPRRTKLAFD DRNYSADHYL QEAKKLKHNA DALSDRFEKA VYYLDAVVSF IECGNALEKN
AQESKSPFLM YSETVELIKY TMKLKNYLAP DATAADKRLT VLCLRCQSLL YLRLFKLKKE
NALKYSKTLT EHLKNSYNNS QAPSPGLGSK AVGMPSPVSP KLSPGNSGNY SSGASSASAS
GSSVTIPHRI HQMAASYVQV TSNFLYATEI WDQAEQLSKE QKEFFAELDK VMGPLIFNAS
IMTDLVRYTR QGLHWLRQDA KLIS
//
