ID A0A7J8K8B1_ROUAE Unreviewed; 409 AA.
AC A0A7J8K8B1;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 02-APR-2025, entry version 11.
DE SubName: Full=Failed axon connections-like protein, metaxin like GST domain containing {ECO:0000313|EMBL:KAF6505104.1};
GN ORFNames=HJG63_004977 {ECO:0000313|EMBL:KAF6505104.1};
OS Rousettus aegyptiacus (Egyptian fruit bat) (Pteropus aegyptiacus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea;
OC Pteropodidae; Rousettinae; Rousettus.
OX NCBI_TaxID=9407 {ECO:0000313|EMBL:KAF6505104.1, ECO:0000313|Proteomes:UP000593571};
RN [1] {ECO:0000313|EMBL:KAF6505104.1, ECO:0000313|Proteomes:UP000593571}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MRouAeg1 {ECO:0000313|EMBL:KAF6505104.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAF6505104.1};
RX PubMed=32699395;
RA Jebb D., Huang Z., Pippel M., Hughes G.M., Lavrichenko K., Devanna P.,
RA Winkler S., Jermiin L.S., Skirmuntt E.C., Katzourakis A., Burkitt-Gray L.,
RA Ray D.A., Sullivan K.A.M., Roscito J.G., Kirilenko B.M., Davalos L.M.,
RA Corthals A.P., Power M.L., Jones G., Ransome R.D., Dechmann D.K.N.,
RA Locatelli A.G., Puechmaille S.J., Fedrigo O., Jarvis E.D., Hiller M.,
RA Vernes S.C., Myers E.W., Teeling E.C.;
RT "Six reference-quality genomes reveal evolution of bat adaptations.";
RL Nature 583:578-584(2020).
CC -!- SIMILARITY: Belongs to the FAX family. {ECO:0000256|ARBA:ARBA00006475}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF6505104.1}.
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DR EMBL; JACASE010000001; KAF6505104.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7J8K8B1; -.
DR KEGG; ray:107514363; -.
DR CTD; 84553; -.
DR OrthoDB; 5809458at2759; -.
DR Proteomes; UP000593571; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR CDD; cd03193; GST_C_Metaxin; 1.
DR CDD; cd03080; GST_N_Metaxin_like; 1.
DR InterPro; IPR026928; FAX/IsoI-like.
DR InterPro; IPR045796; FAXC_N.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR033468; Metaxin_GST.
DR InterPro; IPR050931; Mito_Protein_Transport_Metaxin.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR12289:SF76; FAILED AXON CONNECTIONS HOMOLOG; 1.
DR PANTHER; PTHR12289; METAXIN RELATED; 1.
DR Pfam; PF19333; FAXC_N; 1.
DR Pfam; PF17171; GST_C_6; 1.
DR Pfam; PF17172; GST_N_4; 1.
DR SFLD; SFLDG01180; SUF1; 1.
DR SFLD; SFLDG01200; SUF1.1; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000593571}.
FT DOMAIN 1..106
FT /note="Failed axon connections homolog N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19333"
FT DOMAIN 117..211
FT /note="Thioredoxin-like fold"
FT /evidence="ECO:0000259|Pfam:PF17172"
FT DOMAIN 264..326
FT /note="Metaxin glutathione S-transferase"
FT /evidence="ECO:0000259|Pfam:PF17171"
SQ SEQUENCE 409 AA; 46769 MW; 98B3737ACA824BD8 CRC64;
MHWGVGFASS RPCVVDLSWN QSVSFFGWWA GSEEPFSFYG DIIAFPLQDY GGIMAGLGSD
PWWKKTLYLT GGALLAAAAY LLHELLVIRK QQEIDSKDAI ILHQFARPNN GVPSLSPFCL
KMETYLRMAD LPYQNYFGGK LSAQGKMPWI EYNHEKVSGT EFIIDFLEEK LGVNLNKNLG
PHERAISRAV TKMVEEHFYW TLAYCQWVDN LNETRKMLSL SGGGPFSNLL RWVVCHITKG
IVKREMHGHG IGRFSEEEIY MLMEKDMRSL AGLLGDKKYI MGPKLSTLDA TVFGHLAQAM
WTLPGTRPER LIKGELINLA MYCERIRRKF WPEWHHDDDN TIYESEESSE GSKTHTPLLD
FSFYSRTETF EDEGAENSFS RTPDTDFTGH SLFDSDVDMD DCTDHEQCK
//
