ID A0A7K4PEQ1_MELMO Unreviewed; 499 AA.
AC A0A7K4PEQ1;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 05-FEB-2025, entry version 9.
DE SubName: Full=PIGS transamidase {ECO:0000313|EMBL:NWQ47501.1};
DE Flags: Fragment;
GN Name=Pigs {ECO:0000313|EMBL:NWQ47501.1};
GN ORFNames=MELMEL_R10918 {ECO:0000313|EMBL:NWQ47501.1};
OS Melospiza melodia (Song sparrow) (Fringilla melodia).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Passerellidae; Melospiza.
OX NCBI_TaxID=44397 {ECO:0000313|EMBL:NWQ47501.1, ECO:0000313|Proteomes:UP000560247};
RN [1] {ECO:0000313|EMBL:NWQ47501.1, ECO:0000313|Proteomes:UP000560247}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OUT-0008 {ECO:0000313|EMBL:NWQ47501.1};
RC TISSUE=Blood {ECO:0000313|EMBL:NWQ47501.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}.
CC -!- SIMILARITY: Belongs to the PIGS family.
CC {ECO:0000256|ARBA:ARBA00005316}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NWQ47501.1}.
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DR EMBL; VZSA01000026; NWQ47501.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K4PEQ1; -.
DR UniPathway; UPA00196; -.
DR Proteomes; UP000560247; Unassembled WGS sequence.
DR GO; GO:0042765; C:GPI-anchor transamidase complex; IEA:InterPro.
DR GO; GO:0016255; P:attachment of GPI anchor to protein; IEA:InterPro.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR019540; PtdIno-glycan_biosynth_class_S.
DR PANTHER; PTHR21072; GPI TRANSAMIDASE COMPONENT PIG-S; 1.
DR PANTHER; PTHR21072:SF13; GPI TRANSAMIDASE COMPONENT PIG-S; 1.
DR Pfam; PF10510; PIG-S; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000560247};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 463..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NWQ47501.1"
FT NON_TER 499
FT /evidence="ECO:0000313|EMBL:NWQ47501.1"
SQ SEQUENCE 499 AA; 54674 MW; 42E2EF361507B69E CRC64;
AGPVQVQLVV PMAVVFAPGS VPRDLPRPLP FRDVQEMEIS VNLRSSVTSR YEMRYRSTTA
QEEAALAAAT AREADAALYP LQDTTLGSLT MYVVPETSSL LPQGINVYVG KHRSALLRAE
GGLAALQARL REVTQLMSFT ATSIAAALSD RVPDGQLGPD ARRSLKSSLG YEITFSLLNP
DPKSHTVDWD IEGAVNRFVK PVLDKLSLVA NFSVDSQILY YAVLGVTPRY DKESSSFLLS
AHSLPHVINP VEARLGSSAA SLYPVLNFLL YVPERSHSPL YIQDKDGAPV STNAFHSPRW
GGIMVYNVEA PASPQASLPV HVDVDMARVM EVFLAQLRLL FGLSREEVPP EFLLESPGNE
GLADWELDHL LWAHTVENIA TVSTTLTSLA QLLDKIGNIV IKDDVASEVY RAVASVQSAV
TELSLGHLLA AFQASKEAVT CSERAFFDPS LLHLLYFPDD QKFAIYIPLF LPMAVPILLS
LAKIVRETRL RKKEPTKMD
//
