ID A0A7K4UNE0_9SYLV Unreviewed; 936 AA.
AC A0A7K4UNE0;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 18-JUN-2025, entry version 16.
DE RecName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000256|ARBA:ARBA00069395};
DE Flags: Fragment;
GN Name=Sart3 {ECO:0000313|EMBL:NWR11806.1};
GN ORFNames=SINWEB_R03860 {ECO:0000313|EMBL:NWR11806.1};
OS Sinosuthora webbiana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Sylvioidea; Sylviidae; Sinosuthora.
OX NCBI_TaxID=337173 {ECO:0000313|EMBL:NWR11806.1, ECO:0000313|Proteomes:UP000580691};
RN [1] {ECO:0000313|EMBL:NWR11806.1, ECO:0000313|Proteomes:UP000580691}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-002-08 {ECO:0000313|EMBL:NWR11806.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NWR11806.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}. Nucleus, Cajal body
CC {ECO:0000256|ARBA:ARBA00004408}. Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NWR11806.1}.
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DR EMBL; VXBN01016017; NWR11806.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K4UNE0; -.
DR OrthoDB; 360390at2759; -.
DR Proteomes; UP000580691; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd12391; RRM1_SART3; 1.
DR CDD; cd12392; RRM2_SART3; 1.
DR FunFam; 1.25.40.10:FF:000081; squamous cell carcinoma antigen recognized by T-cells 3; 1.
DR FunFam; 1.25.40.10:FF:000098; Squamous cell carcinoma antigen recognized by T-cells 3; 1.
DR FunFam; 3.30.70.330:FF:000229; Squamous cell carcinoma antigen recognized by T-cells 3; 1.
DR FunFam; 3.30.70.330:FF:000271; squamous cell carcinoma antigen recognized by T-cells 3; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR008669; LSM_interact.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034217; SART3_RRM1.
DR InterPro; IPR034218; SART3_RRM2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR17204; PRE-MRNA PROCESSING PROTEIN PRP39-RELATED; 1.
DR PANTHER; PTHR17204:SF25; RRM DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF23241; HAT_PRP39_C; 1.
DR Pfam; PF23240; HAT_PRP39_N; 1.
DR Pfam; PF16605; LSM_int_assoc; 1.
DR Pfam; PF05391; Lsm_interact; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00386; HAT; 7.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000580691};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 677..755
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 774..851
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 562..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 889..936
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..54
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..587
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 605..616
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..663
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NWR11806.1"
FT NON_TER 936
FT /evidence="ECO:0000313|EMBL:NWR11806.1"
SQ SEQUENCE 936 AA; 106753 MW; 7F46811291B4926E CRC64;
GRRAELHKMA AAGAEAAAEE EKRLPEGDPE SGGDSDDEGD SDSSGDGEDE EKENEAEIQR
LEEQLSINAF DYNCHLDLIK LLRQEGELVK LRRARQKMSE LFPLTEEIWL DWLKDEIKMA
SEISEREKVY ELFERAVKDY ICPEIWLEYA QYSIGGIGQE GGIERVRSIF ERALTAVGLH
VTKGTALWEA YREFENAILE TAQPAPGSIP SPEQQQVLCS QLEKIHTLFR RQLGIPLLDM
EASYAEYEEW SEEPIPEATI KNYKKALQQL EKCKPYEEAL LGAETPKLAE YQAYIDFEMK
AGDPARIQLI YERALAENCL VPDLWARYNQ YLDRQLKVKE LVLSAHDRAV RNCPWTVGLW
IRYLLAMERH RVEHSIISEM FEKALNAGFI QATDYVEIWQ AYLDYLRRRV DFTQDSSKEL
EELRSAFARA VEYLKQEVEE RFSESGDPSC TIMQNWARVE ARLCNNMQKA RELWDNIMTK
GNAKYANMWL EYYNLERAHG DTQHCRKALH RAVQCTSDYP EHVCEVLLTL ERIEGTLEDW
DAAVQKTENR LARVNEQRAK AAEKEAALAK QEEERAEQRK QARAEKKASK KAKKTRIGDK
RKADEDDEGE WGQEEELPSK RHRGEGDGVL PEEDMEVESG LFGRSEKPDG PAIPKEKAST
SRRDIPKVFH DSSKDKVTVF VSNLSYTMAE PEAKLRELFG SCGEVVEIRA VFNNKGTFRG
YGYVQFKEEE AARQALALDR TAVEGRPMFV SPCVDKNKNP DFKVFRYSTT LEKHKLFISG
LPFSCTKEEL EEVCKAHGNV KDIRLVTNRA GKPKGLAYVE YENEAQASQA VLKMDGLTVK
DHVIKVMISN PPLRKLPDRP EPGRASLALA PRQIYGARGK GRTQLSMMPR ALQRQSNPVA
KAENGMVQNS PAASSEPPAE PKKMSNADFA KMLLKK
//
