ID A0A7K4YWR7_BUCAB Unreviewed; 958 AA.
AC A0A7K4YWR7;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 10-JUN-2026, entry version 16.
DE SubName: Full=SYDE2 protein {ECO:0000313|EMBL:NWR63287.1};
DE Flags: Fragment;
GN Name=Syde2 {ECO:0000313|EMBL:NWR63287.1};
GN ORFNames=BUCABY_R01781 {ECO:0000313|EMBL:NWR63287.1};
OS Bucorvus abyssinicus (Northern ground-hornbill) (Abyssinian
OS ground-hornbill).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Coraciimorphae;
OC Bucerotiformes; Bucorvidae; Bucorvus.
OX NCBI_TaxID=153643 {ECO:0000313|EMBL:NWR63287.1, ECO:0000313|Proteomes:UP000551127};
RN [1] {ECO:0000313|EMBL:NWR63287.1, ECO:0000313|Proteomes:UP000551127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-012-80 {ECO:0000313|EMBL:NWR63287.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NWR63287.1}.
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DR EMBL; VYZL01004187; NWR63287.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K4YWR7; -.
DR OrthoDB; 120383at2759; -.
DR Proteomes; UP000551127; Unassembled WGS sequence.
DR GO; GO:0097060; C:synaptic membrane; IEA:TreeGrafter.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0016477; P:cell migration; IEA:TreeGrafter.
DR GO; GO:0046578; P:regulation of Ras protein signal transduction; IEA:TreeGrafter.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR FunFam; 1.10.555.10:FF:000031; rho GTPase-activating protein 100F isoform X6; 1.
DR FunFam; 2.60.40.150:FF:000195; Synapse defective Rho GTPase homolog 2; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR052118; Rho-GAP_regulator.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR057459; SYDE1/2_C2.
DR PANTHER; PTHR46150; RHO GTPASE-ACTIVATING PROTEIN 100F; 1.
DR PANTHER; PTHR46150:SF1; RHO GTPASE-ACTIVATING PROTEIN SYDE2; 1.
DR Pfam; PF25336; C2_SYDE; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468, ECO:0000256|PROSITE-
KW ProRule:PRU00172}; Reference proteome {ECO:0000313|Proteomes:UP000551127}.
FT DOMAIN 424..543
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 580..795
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 40..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 253..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 296..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 365..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 832..852
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 874..907
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 400..411
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..888
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..900
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NWR63287.1"
FT NON_TER 958
FT /evidence="ECO:0000313|EMBL:NWR63287.1"
SQ SEQUENCE 958 AA; 105760 MW; 97520411DE8B8EF3 CRC64;
DLIENVYIAS RSRKEPRSPQ ANEVPEHRLQ VNSITVSKKR SWLQQSTCRP PPPPPEEENA
YKETHGCIIP VPKSPIPLPE PGVLQAPSMS LVGQECPTQS CGPVSALQST TSPAAPRSAA
FNFGEDNDAD DEGEIWYNPI PEDDEPDLLR VPLSAVNSPV AVGSPLVRYK PLSGGGSGMA
MGSYKGLPCS MESVANSWTA QPSEASQADA AHPREHVQQH WQKFACKAPS VLAVEDNPVF
KCPSTGSGVV LAHKTDTSST EVSPPSPSPL KKSGSINWPF PDRIKSPRTV RKLSMKMKKL
PELSRKLSVK GTSSHTSSDN PPSLLKGSSQ DTSHTVSLPS SGNSTTAASR NVISRYHLDS
SVLSQHTYKK KNSRTSKSFS KGGYLSDGDS PELITKSGKH GHETKCGKGK ESLPSNSGKT
EIDIDAFRHY NFSDQPKCSQ YISGLMSIHF YGAEDLKPPR IDSKDVFCAI QVDSVNKART
ALLTCRTTFL DMDHTFNIEI ENAQHLKLVV FSWEPTPRKN RVCCHGTVAL PTLFRVTKTH
QLAVKLEPRG LIYVKLSLME QWENSLDGLD ADREPVMFGV DARQVVEKEN TGLMVPLLME
KCILEIEKRG CQVVGLYRLC GSAAVKKELR EAFERDSKAV TLCESQYPDI NVITGVLKDY
LRELPSPLIT KQLYEAVLDA MVKNPLKMTA SGCENDPSDS EHTAALLDCL PDVEKATLKM
LLDHLKLVAS YHEVNKMTCQ NLAVCFGPVL LSQRQETTNH NNRVFTDSEE LASALDFKKH
IEVLHYLLQL WPVHHSPAKE AAHLNAFPEH SSSLNYLRPR RQRPQMLNLS GAEMSGVLRP
RPAGLDSPSS NRYAGDWSSC GENYLNSKDC LSEADYDDVP SEDTESGDDC SKAEESDAAV
RHPQPIPREH TFQNYLTMQA IDPAVDHRAN LKDLQESIDT LIGNLERELN KNKLNMSY
//
