ID A0A7K5T416_9FRIN Unreviewed; 226 AA.
AC A0A7K5T416;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 08-OCT-2025, entry version 16.
DE SubName: Full=HES6 protein {ECO:0000313|EMBL:NWT98525.1};
DE Flags: Fragment;
GN Name=Hes6 {ECO:0000313|EMBL:NWT98525.1};
GN ORFNames=UROPYL_R14559 {ECO:0000313|EMBL:NWT98525.1};
OS Urocynchramus pylzowi.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Passeroidea; Fringillidae; Urocynchramus.
OX NCBI_TaxID=571890 {ECO:0000313|EMBL:NWT98525.1, ECO:0000313|Proteomes:UP000524542};
RN [1] {ECO:0000313|EMBL:NWT98525.1, ECO:0000313|Proteomes:UP000524542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-012-38 {ECO:0000313|EMBL:NWT98525.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NWT98525.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NWT98525.1}.
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DR EMBL; VZRH01004587; NWT98525.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K5T416; -.
DR Proteomes; UP000524542; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd11410; bHLH_O_HES; 1.
DR FunFam; 4.10.280.10:FF:000009; Transcription factor HES-1; 1.
DR Gene3D; 6.10.250.980; -; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR050370; HES_HEY.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR003650; Orange_dom.
DR PANTHER; PTHR10985; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED; 1.
DR Pfam; PF07527; Hairy_orange; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF158457; Orange domain-like; 1.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS51054; ORANGE; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000524542};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 18..72
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 91..124
FT /note="Orange"
FT /evidence="ECO:0000259|PROSITE:PS51054"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 132..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NWT98525.1"
FT NON_TER 226
FT /evidence="ECO:0000313|EMBL:NWT98525.1"
SQ SEQUENCE 226 AA; 25531 MW; 93D4E6C0B54156AF CRC64;
MTAAATTGTH KVASTKEERK LRKPLIERKR RERINNCLDQ LKETVVGAFH LDQSKLEKAD
ILEMTVKHLQ NIQSSKMMAD SKVGLEAQQR YSTGYIQCMH EVHNLLLTCE WMDKSLGARL
LNHLLKSLPG PGEDSCKAAL RSGSPSQQPL RTQRSPLSPK GSARGTNPPQ ERLYPAENKQ
ASKNFFQLPS LSHFNQVDAA PPRQVLQPNF SHNNPRMGSL DMWRPW
//
