ID A0A7K6I1F9_9PASS Unreviewed; 495 AA.
AC A0A7K6I1F9;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 05-FEB-2025, entry version 9.
DE SubName: Full=PIGS transamidase {ECO:0000313|EMBL:NWV81122.1};
DE Flags: Fragment;
GN Name=Pigs {ECO:0000313|EMBL:NWV81122.1};
GN ORFNames=DASBRO_R00213 {ECO:0000313|EMBL:NWV81122.1};
OS Dasyornis broadbenti (rufous bristle-bird).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Meliphagoidea; Dasyornithidae; Dasyornis.
OX NCBI_TaxID=243059 {ECO:0000313|EMBL:NWV81122.1, ECO:0000313|Proteomes:UP000521322};
RN [1] {ECO:0000313|EMBL:NWV81122.1, ECO:0000313|Proteomes:UP000521322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-029-49 {ECO:0000313|EMBL:NWV81122.1};
RC TISSUE=Liver {ECO:0000313|EMBL:NWV81122.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}.
CC -!- SIMILARITY: Belongs to the PIGS family.
CC {ECO:0000256|ARBA:ARBA00005316}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NWV81122.1}.
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DR EMBL; VZRN01004159; NWV81122.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K6I1F9; -.
DR UniPathway; UPA00196; -.
DR Proteomes; UP000521322; Unassembled WGS sequence.
DR GO; GO:0042765; C:GPI-anchor transamidase complex; IEA:InterPro.
DR GO; GO:0016255; P:attachment of GPI anchor to protein; IEA:InterPro.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR019540; PtdIno-glycan_biosynth_class_S.
DR PANTHER; PTHR21072; GPI TRANSAMIDASE COMPONENT PIG-S; 1.
DR PANTHER; PTHR21072:SF13; GPI TRANSAMIDASE COMPONENT PIG-S; 1.
DR Pfam; PF10510; PIG-S; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000521322};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 459..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NWV81122.1"
FT NON_TER 495
FT /evidence="ECO:0000313|EMBL:NWV81122.1"
SQ SEQUENCE 495 AA; 54052 MW; B77B9FAF3EDC6538 CRC64;
QVQLVVPIAV VFGPGSVPGD LPRPLPFGDV QEMEISVNLR TSVTSRYEML YRSTTGQEEA
ALAAATAREA DAALHPLQDT TLGSLTMYVV SETSSLLPQG INVYVGKHRS ALVRAVGSLA
ALQARLQEVT QVMSFTASSI AAALSDRVPN GQLSPDARRY LKSSLGYEIT FSLLNPDPKS
HAVDWDIEGA VNCYVKPVLD KLSLVANFSV DSQILYYAVL GVTPRYDKES SSFLLSAHSL
PHVINPVEAR LGSSAASLYP VLNFLLYVPE RSHSPLYIQD KDGAPVSTNA FHSPRWGGIM
VYNTEAPASS QASLPLHVDV DMARVMEVFL AQLRLLFGLS REELPPEFLL ESPGNEGLAD
WELDHLLWAH TVENIATVST TLTSLAQLLD KIGNIVIKDD VASEVYRAVA SVQSAMAKLS
LGHLHAAFQA SKEAVTSSER AFFDPSLLHL LYFPDDQKFA IYIPLFLPMA VPILLSLAKI
VRETRQRKKE PTKMD
//
