ID A0A7K7SBL9_9PASS Unreviewed; 215 AA.
AC A0A7K7SBL9;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 08-OCT-2025, entry version 14.
DE RecName: Full=Syntaxin-binding protein 6 {ECO:0000256|ARBA:ARBA00069758};
DE Flags: Fragment;
GN Name=Stxbp6 {ECO:0000313|EMBL:NXA01132.1};
GN ORFNames=NESACU_R03058 {ECO:0000313|EMBL:NXA01132.1};
OS Nesospiza acunhae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Thraupidae; Nesospiza.
OX NCBI_TaxID=381881 {ECO:0000313|EMBL:NXA01132.1, ECO:0000313|Proteomes:UP000549091};
RN [1] {ECO:0000313|EMBL:NXA01132.1, ECO:0000313|Proteomes:UP000549091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OUT-0053 {ECO:0000313|EMBL:NXA01132.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXA01132.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Forms non-fusogenic complexes with SNAP25 and STX1A and may
CC thereby modulate the formation of functional SNARE complexes and
CC exocytosis. {ECO:0000256|ARBA:ARBA00055117}.
CC -!- SUBUNIT: Part of a ternary complex containing SNAP25 and STX1A that can
CC be dissociated by NAPA and NSF. Interacts with STX4A.
CC {ECO:0000256|ARBA:ARBA00065733}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXA01132.1}.
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DR EMBL; VZSU01002948; NXA01132.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K7SBL9; -.
DR Proteomes; UP000549091; Unassembled WGS sequence.
DR GO; GO:0000145; C:exocyst; IEA:TreeGrafter.
DR GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:TreeGrafter.
DR GO; GO:0006887; P:exocytosis; IEA:TreeGrafter.
DR GO; GO:0006893; P:Golgi to plasma membrane transport; IEA:TreeGrafter.
DR CDD; cd14681; PH-STXBP6; 1.
DR FunFam; 1.20.5.110:FF:000029; Syntaxin-binding protein 6; 1.
DR FunFam; 2.30.29.90:FF:000002; syntaxin-binding protein 6; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR Gene3D; 2.30.29.90; -; 1.
DR InterPro; IPR028258; Sec3-PIP2_bind.
DR InterPro; IPR037821; STXBP6_PH.
DR InterPro; IPR042855; V_SNARE_CC.
DR PANTHER; PTHR16092:SF14; EXOCYST COMPLEX COMPONENT 1 ISOFORM X1; 1.
DR PANTHER; PTHR16092; SEC3/SYNTAXIN-RELATED; 1.
DR Pfam; PF15277; Sec3-PIP2_bind; 1.
DR Pfam; PF00957; Synaptobrevin; 1.
DR SMART; SM01313; Sec3-PIP2_bind; 1.
DR SUPFAM; SSF58038; SNARE fusion complex; 1.
DR PROSITE; PS50892; V_SNARE; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PROSITE-
KW ProRule:PRU00290}; Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000549091}.
FT DOMAIN 159..215
FT /note="V-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50892"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXA01132.1"
FT NON_TER 215
FT /evidence="ECO:0000313|EMBL:NXA01132.1"
SQ SEQUENCE 215 AA; 24285 MW; AF17637FB3505FE0 CRC64;
MNAKSAISKE IFAPHDERML GAVQVKRRTK KKIPFLATGG QGEYLTYICL SVICFSICSV
TNKKPAQASI TKVKQFEGST SFVRRTQWML EQLRQVNGID PNRDSPEFDL LFENAFDQWV
ANTASEKCTF FQVLHHTCQR YLTDKKPEFI NCQSKIMGGN SILHSAADSV TSAVQKASQA
LNERGERLGR AEEKTEELKN SAQQFAETAH KVRFQ
//
