ID A0A7K7YFA3_THRLU Unreviewed; 403 AA.
AC A0A7K7YFA3;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE SubName: Full=CRDL2 protein {ECO:0000313|EMBL:NXA76666.1};
DE Flags: Fragment;
GN Name=Chrdl2 {ECO:0000313|EMBL:NXA76666.1};
GN ORFNames=THRLUD_R04134 {ECO:0000313|EMBL:NXA76666.1};
OS Thryothorus ludovicianus (Carolina wren) (Sylvia ludoviciana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Certhiidae; Troglodytinae; Thryothorus.
OX NCBI_TaxID=74200 {ECO:0000313|EMBL:NXA76666.1, ECO:0000313|Proteomes:UP000558509};
RN [1] {ECO:0000313|EMBL:NXA76666.1, ECO:0000313|Proteomes:UP000558509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B10K-DU-001-68 {ECO:0000313|EMBL:NXA76666.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXA76666.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXA76666.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; VZTB01007419; NXA76666.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A7K7YFA3; -.
DR Proteomes; UP000558509; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0036122; F:BMP binding; IEA:TreeGrafter.
DR GO; GO:0030154; P:cell differentiation; IEA:TreeGrafter.
DR GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:TreeGrafter.
DR GO; GO:0048731; P:system development; IEA:UniProtKB-ARBA.
DR FunFam; 2.10.70.10:FF:000005; Chordin-like 1, isoform CRA_c; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 2.
DR InterPro; IPR045717; CHRDL1/2.
DR InterPro; IPR045716; CHRDL_1/2_C.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR46303:SF3; CHORDIN-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR46303; VWFC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF19548; CHRDL_1_2_C; 1.
DR Pfam; PF00093; VWC; 1.
DR Pfam; PF23334; VWC2L_2nd; 1.
DR SMART; SM00214; VWC; 2.
DR SUPFAM; SSF57603; FnI-like domain; 2.
DR PROSITE; PS01208; VWFC_1; 1.
DR PROSITE; PS50184; VWFC_2; 2.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000558509};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 79..145
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 220..285
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXA76666.1"
FT NON_TER 403
FT /evidence="ECO:0000313|EMBL:NXA76666.1"
SQ SEQUENCE 403 AA; 44921 MW; 22498129174FBF75 CRC64;
PDTFCDFNGK KYSPGESWHP YLEPQGLMYC IRCSCSEARA AAGASLLRWG QARAGSHPAP
FSPSFPEPHS PSGLRAPAKS CQHNGTTYQQ GEMFSSSELF PGRQPNQCVQ CSCSEGQIYC
GLVTCPELLC SSPLTVPDSC CQVCKDGSFE KSTEEEPLQL NRGVRHSQDQ CLGEVVGRKP
PGATVSTVLS SSLELIPRSF KPKGTGGTTV KIVLKEKHKK ACVYNGKTYS HGEVWHPVFR
LYGLLPCILC TCRDGVQDCQ KITCPKEYPC EHPEKVDGKC CKICPEARVK PTEEVTTARC
GKSPSRVLVY TFVPPRSEAS KEILRTMAIE KELAEEVEIY NWKLIKGIFH LIQTKKISKQ
EFKQEAQNFR LITRTNEGHW NIFRAQTSEL KMTESPEKET KNL
//
